Evidence map›Paper›PMID 28286906›Full record

ArticleCurrent microbiology2017

Selection of Cholesterol-Lowering Lactic Acid Bacteria and its Effects on Rats Fed with High-Cholesterol Diet.

Yufang Liu, Fengchun Zhao, Jiye Liu, Huimin Wang, Xiao Han, Yongxin Zhang, Zhengyou Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Impact of Dietary Interventions withFoods (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Effects of cholesterol and Lactobacillus acidophilus on testicular function.Clinical and experimental reproductive medicine · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. Isolation of aKorean journal for food science of animal resources · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yufang LiuKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Fengchun ZhaoKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Jiye LiuKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Huimin WangKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Xiao HanKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Yongxin ZhangKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China.
Zhengyou YangKey Laboratory for Agricultural Microbiology, Department of Microbiology College of Life Science, Shandong Agricultural University, Taian, 271000, China. zhyouyang@sdau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High cholesterol level in serum is a major factor of influence for coronary heart disease. The cholesterol-lowering ability of lactic acid bacteria (LAB) without side effects makes them more and more attractive. Seventy-nine strains of LAB isolated from fermented food were screened in vitro for their ability to assimilate cholesterol. Then, ten strains which exhibited higher ability of cholesterol assimilation were investigated with the characteristics of acidic resistance, bile salt tolerance, and cell adhesion. According to the results, the best strain LP96 was picked out, and used to evaluate its effects on the high-cholesterol diet-fed rats. The results demonstrated that the levels of serum triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol, and liver TC and TG were reduced significantly in the groups that received the strain LP96 solution compared with the model group, and that the serum high-density lipoprotein cholesterol levels were increased without any significant difference. Furthermore, LP96 also showed good antioxidative activity and improvement of intestinal microbial balance in the rats. Thus, LP96 may be a promising probiotics with potential cholesterol-lowering ability.

Indexed as

Animal FeedDiet, High-FatProbioticsAdaptation, BiologicalAnimalsAntioxidantsBacterial AdhesionBile Acids and SaltsBody WeightCholesterolGastrointestinal MicrobiomeLactobacillusLipid MetabolismLiverPhylogenyRatsAntioxidantsBile Acids and SaltsCholesterol

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.