ReviewPediatric nephrology (Berlin, Germany)2018
The molecular biology of pelvi-ureteric junction obstruction.
Review in Pediatric nephrology (Berlin, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Comparing accuracy of urinary biomarkers in differentiation of ureteropelvic junction obstruction from nonobstructive dilatation in children.Pediatric nephrology (Berlin, Germany) · 2022Pooled it
- Ultrasonographic changes following pyeloplasty in children with ureteropelvic junction obstruction: a prospective observational before-after cohort study.Annals of medicine and surgery (2012) · 2026Article
- TGF-β1 induces epithelial-mesenchymal transition and fibrosis of ureteral epithelial cells via targeting RACK1 in ureteropelvic junction obstruction.Translational pediatrics · 2026Article
- A Bibliometric Analysis of Research Trends in Paediatric Pelvic-Ureteric Junction Obstruction.Cureus · 2025Review
- Stromal vascular fraction inhibits renal fibrosis by regulating metabolism and inflammation in obstructive nephropathy.Frontiers in pharmacology · 2025Article
- Dimethyl malonate alleviates obstructive nephropathy by enhancing renal metabolism and inhibiting kidney oxidative stress and inflammation.Frontiers in pharmacology · 2025Article
- Accuracy of Sonographic Renal Pelvic Diameter in Assessment of Renal Function among Patients with Ureteropelvic Junction Obstruction using Scintigraphy as a Gold Standard.International journal of medical sciences · 2025Article
- Succinate Facilitates CD4Journal of inflammation research · 2025Article
- Degree of kidney injury due to artificial pelvic-ureteric junction obstruction with level of neutrophil gelatinase-associated lipocalin, interleukin 18, and histopathological descriptions in Wistar: experimental research.Annals of medicine and surgery (2012) · 2023Article
- Radiological and surgical correlation of pelviureteric junction obstruction in positional anomalies of the kidney in children.Pediatric radiology · 2023Article
- Expression and clinical implications of PARs in the stenotic tissue of ureteropelvic junction obstruction.Frontiers in pediatrics · 2023Article
- Understanding ureteropelvic junction obstruction: how far have we come?Frontiers in urology · 2023Review
- A Comparative Analysis of Robot-Assisted Laparoscopic Pyeloplasty in Pediatric and Adult Patients: Does Age Matter?Journal of clinical medicine · 2022Article
- Chronic Kidney Disease in Boys with Posterior Urethral Valves-Pathogenesis, Prognosis and Management.Biomedicines · 2022Review
- Exosomal proteomics in kidney disease: From technical approaches to clinical applications.Journal of food and drug analysis · 2022Review
- Evaluation of PGP 9.5, NGFR, TGFβ1, FGFR1, MMP-2, AT2R2, SHH, and TUNEL in Primary Obstructive Megaureter Tissue.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2022Article
- Renal Cortical Thickness After Pyeloplasty in Pediatric Ureteropelvic Junction Obstruction.Research and reports in urology · 2021Article
- Minimal Invasive Treatment in Pelvic-Ureteric Junction Obstruction: A Comprehensive Review.Research and reports in urology · 2021Review
- The Genomic Response to TGF-β1 Dictates Failed Repair and Progression of Fibrotic Disease in the Obstructed Kidney.Frontiers in cell and developmental biology · 2021Review
- Screening for Renal and Urinary Tract Anomalies in Asymptomatic First Degree Relatives of Children with Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).Indian journal of pediatrics · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Over recent years routine ultrasound scanning has identified increasing numbers of neonates as having hydronephrosis and pelvi-ureteric junction obstruction (PUJO). This patient group presents a diagnostic and management challenge for paediatric nephrologists and urologists. In this review we consider the known molecular mechanisms underpinning PUJO and review the potential of utilising this information to develop novel therapeutics and diagnostic biomarkers to improve the care of children with this disorder.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.