ArticleJournal of immunology research2017
Computational Approaches to Facilitate Epitope-Based HLA Matching in Solid Organ Transplantation.
Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- PIRCHE-II Is Related to Graft Failure after Kidney Transplantation.Frontiers in immunology · 2018Trial
- Simulation of prospective PIRCHE-II molecular matching in Canada: a feasibility study.Frontiers in immunology · 2026Article
- HLA Type and the Effect of HLA Antibodies in Kidney, Liver, and Pancreas Transplantation: A Review.Avicenna journal of medical biotechnology · 2026Review
- Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compatibility.Frontiers in immunology · 2025Article
- Article
- Comprehensive Characterization of Anti-HLA and Non-HLA Antibodies in Patients on Kidney Transplant Waiting List and Evaluation of Their Impact on Alloimmunization Risk and Dialysis Treatment.International journal of molecular sciences · 2024Article
- Positive Long-Term Outcome of Kidney Allocation via Acceptable Mismatch Program in Highly Sensitized Patients.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2024Article
- Expression of Rejection-Associated Transcripts in Early Protocol Renal Transplant Biopsies Is Associated with Tacrolimus Exposure and Graft Outcome.International journal of molecular sciences · 2024Article
- Quantifying uncertainty of molecular mismatch introduced by mislabeled ancestry using haplotype-based HLA genotype imputation.Frontiers in genetics · 2024Article
- Improving long-term kidney allograft survival by rethinking HLA compatibility: from molecular matching to non-HLA genes.Frontiers in genetics · 2024Review
- An Integrated Approach Using HLAMatchmaker and Pirche II for Epitopic Matching in Pediatric Kidney Transplant-A Romanian Single-Center Study.Children (Basel, Switzerland) · 2023Article
- Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation.Frontiers in immunology · 2022Article
- Snowflake: A deep learning-based human leukocyte antigen matching algorithm considering allele-specific surface accessibility.Frontiers in immunology · 2022Article
- The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation.Frontiers in immunology · 2022Article
- Computational Eurotransplant kidney allocation simulations demonstrate the feasibility and benefit of T-cell epitope matching.PLoS computational biology · 2021Article
- T-Cell Epitopes Shared Between Immunizing HLA and Donor HLA Associate With Graft Failure After Kidney Transplantation.Frontiers in immunology · 2021Article
- Can PIRCHE-II Matching Outmatch Traditional HLA Matching?Frontiers in immunology · 2021Article
- PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantation.Immunogenetics · 2020Review
- Single haplotype admixture models using large scale HLA genotype frequencies to reproduce human admixture.Immunogenetics · 2019Article
- Predicting kidney transplant outcomes with partial knowledge of HLA mismatch.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epitope-based HLA matching has been emerged over the last few years as an improved method for HLA matching in solid organ transplantation. The epitope-based matching concept has been incorporated in both the PIRCHE-II and the HLAMatchmaker algorithm to find the most suitable donor for a recipient. For these algorithms, high-resolution HLA genotype data of both donor and recipient is required. Since high-resolution HLA genotype data is often not available, we developed a computational method which allows epitope-based HLA matching from serological split level HLA typing relying on HLA haplotype frequencies. To validate this method, we simulated a donor-recipient population for which PIRCHE-II and eplet values were calculated when using both high-resolution HLA genotype data and serological split level HLA typing. The majority of the serological split level HLA-determined
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