Evidence map›Paper›PMID 28286778›Full record

ArticleJournal of diabetes research2017

Prognostic Relevance and Function of MSX2 in Colorectal Cancer.

Jiancheng Liu, Huaying An, Wei Yuan, Qiang Feng, Lianzhen Chen, Jie Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Characterization of Epigenomic Alterations in HPV16+ Head and Neck Squamous Cell Carcinomas.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022
    Article
  5. Current issues in molecular biology · 2021
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiancheng LiuState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Huaying AnState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Wei YuanState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China; Clinical Immunology Center, Chinese Academy of Medical Science, Beijing 100730, China.
Qiang FengDepartment of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Lianzhen ChenDepartment of Pharmacy, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.ORCID 0000-0002-2567-5552
Jie MaState Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China; Clinical Immunology Center, Chinese Academy of Medical Science, Beijing 100730, China; Beijing Hospital, National Center of Gerontology, Beijing 100730, China.ORCID 0000-0002-2938-818X
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Traumatic Stress and Alcohol Problems: Between- and Within- Person AssociationsR01AA020519 · NIAAA · UNIVERSITY OF SOUTH DAKOTA · PI SIMONS, JEFFREY S · 2012 to 2015
$1.6M
NIAAA NIH HHS R01 AA020519
6 · The paper itself

Abstract

Colorectal cancer patients with diabetes had the high risks of total mortality. High expression of MSX2 is related to development of diabetes. There are few reports about the clinical implications and function of MSX2 in colorectal cancer (CRC). The purpose of this study is to investigate the relationship between the expression of MSX2 and clinical relevance and discover the possible mechanism of MSX2 in the development of CRC. Compared with adjacent tissues, the expression of MSX2 was higher in tumor tissues in both mRNA and protein levels (

Indexed as

ApoptosisCell Cycle CheckpointsCell Line, TumorCell ProliferationColorectal NeoplasmsDisease ProgressionFemaleHomeodomain ProteinsHumansLymphatic MetastasisMaleMiddle AgedNeoplasm StagingPhosphorylationPrognosisProto-Oncogene Proteins c-aktHomeodomain ProteinsMSX2 proteinProto-Oncogene Proteins c-akt

Identifiers

PMID28286778
PMCPMC5327771
OpenAlexW2586210712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.