Evidence map›Paper›PMID 28286676›Full record

ArticleNeural plasticity2017

Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study.

K Spielmann, R van der Vliet, W M E van de Sandt-Koenderman, M A Frens, G M Ribbers, R W Selles, S van Vugt, J N van der Geest, P Holland

Abstract read
In one paragraph

Article in Neural plasticity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Cerebellar Neuromodulation Impacts Reading Fluency in Young Adults.Neurobiology of language (Cambridge, Mass.) · 2024
    Article
  6. A Brief History of Cerebellar Neurostimulation.Cerebellum (London, England) · 2022
    Review
  7. Article
  8. Article
  9. A narrative review on non-invasive stimulation of the cerebellum in neurological diseases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

K SpielmannRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.ORCID 0000-0003-1259-2704
R van der VlietRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands; Department of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.
W M E van de Sandt-KoendermanRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.
M A FrensDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands; Erasmus University College, Rotterdam, Netherlands.ORCID 0000-0002-0752-2034
G M RibbersRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.
R W SellesRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands; Department of Rehabilitation Medicine, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands; Department of Plastic and Reconstructive Surgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.ORCID 0000-0002-2432-6756
S van VugtRijndam Rehabilitation Institute, P.O. Box 23181, 3001 KD Rotterdam, Netherlands.
J N van der GeestDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands.ORCID 0000-0002-2870-4208
P HollandDepartment of Neuroscience, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, Netherlands; Department of Biomedical Engineering, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of the cerebellum in cognitive processing is increasingly recognized but still poorly understood. A recent study in this field applied cerebellar Transcranial Direct Current Stimulation (c-tDCS) to the right cerebellum to investigate the role of prefrontal-cerebellar loops in language aspects of cognition. Results showed that the improvement in participants' verbal response times on a verb generation task was facilitated immediately after cathodal c-tDCS, compared to anodal or sham c-tDCS. The primary aim of the present study is to replicate these findings and additionally to investigate possible longer term effects. A crossover within-subject design was used, comparing cathodal and sham c-tDCS. The experiment consisted of two visits with an interval of one week. Our results show no direct contribution of cathodal c-tDCS over the cerebellum to language task performance. However, one week later, the group receiving cathodal c-tDCS in the first visit show less improvement and increased variability in their verbal response times during the second visit, compared to the group receiving sham c-tDCS in the first visit. These findings suggest a potential negative effect of c-tDCS and warrant further investigation into long term effects of c-tDCS before undertaking clinical studies with poststroke patients with aphasia.

Indexed as

ReadingAdultCerebellumCross-Over StudiesDouble-Blind MethodFemaleHumansLearningMalePhotic StimulationPilot ProjectsPsychomotor PerformanceReaction TimeTranscranial Direct Current StimulationVerbal BehaviorVocabulary

Identifiers

PMID28286676
PMCPMC5329667

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.