Evidence map›Paper›PMID 28286600›Full record

ArticleJMLR workshop and conference proceedings2016

Doctor AI: Predicting Clinical Events via Recurrent Neural Networks.

Edward Choi, Mohammad Taha Bahadori, Andy Schuetz, Walter F Stewart, Jimeng Sun

Registry-linked trialAbstract read
In one paragraph

Article in JMLR workshop and conference proceedings, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06447532 (Use of Machine Learning Techniques for Serial Assessment of Systemic Inflammatory Markers in Breast Cancer Patients), which is not on this map. Cited by 280 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
280citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06447532 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Use of Machine Learning Techniques for Serial Assessment of Systemic Inflammatory Markers in Breast Cancer Patients

TypeobservationalSponsorFederal University of São PauloRan2024 to 2027Enrolled4,500ConditionsBreast CancerArmsSurgery (Mastectomy or quadrantectomy)
3 · Its place in the literature

Who cites it

280 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Evaluation of trajectory analysis for disease risk assessment: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2026
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220 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Edward ChoiCollege of Computing Georgia Institute of Technology Atlanta, GA, USA.
Mohammad Taha BahadoriCollege of Computing Georgia Institute of Technology Atlanta, GA, USA.
Andy SchuetzResearch Development & Dissemination Sutter Health Walnut Creek, CA, USA.
Walter F StewartResearch Development & Dissemination Sutter Health Walnut Creek, CA, USA.
Jimeng SunCollege of Computing Georgia Institute of Technology Atlanta, GA, USA.

Funding

Early Detection of Heart Failure via the Electronic Health Record in Primary CareR01HL116832 · NHLBI · CALIFORNIA PACIFIC MED CTR RES INSTITUTE · PI STEWART, WALTER F · 2013 to 2015
$1.5M
NHLBI NIH HHS R01 HL116832
6 · The paper itself

Abstract

Leveraging large historical data in electronic health record (EHR), we developed Doctor AI, a generic predictive model that covers observed medical conditions and medication uses. Doctor AI is a temporal model using recurrent neural networks (RNN) and was developed and applied to longitudinal time stamped EHR data from 260K patients over 8 years. Encounter records (e.g. diagnosis codes, medication codes or procedure codes) were input to RNN to predict (all) the diagnosis and medication categories for a subsequent visit. Doctor AI assesses the history of patients to make multilabel predictions (one label for each diagnosis or medication category). Based on separate blind test set evaluation, Doctor AI can perform differential diagnosis with up to 79% recall@30, significantly higher than several baselines. Moreover, we demonstrate great generalizability of Doctor AI by adapting the resulting models from one institution to another without losing substantial accuracy.

Identifiers

PMID28286600
PMCPMC5341604

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.