Evidence map›Paper›PMID 28286572›Full record

ArticleGut pathogens2017

Attenuation of

Nillu Ghosh, Prachetash Ghosh, Kousik Kesh, Asish K Mukhopadhyay, Snehasikta Swarnakar

Open access · goldAbstract read
In one paragraph

Article in Gut pathogens, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Inflammatory factors collaboratively linkFrontiers in immunology · 2025
    Review
  2. Article
  3. A Mouse Model of Helicobacter pylori Infection.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  4. The Exopolysaccharide ofMicroorganisms · 2020
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nillu GhoshCancer Biology and Inflammatory Disorder Division, Indian Institute of Chemical Biology, 4, Raja S.C. Mullik Road, Jadavpur, Kolkata, 700032 India.
Prachetash GhoshNational Institute of Cholera and Enteric Diseases, Kolkata, India.
Kousik KeshCancer Biology and Inflammatory Disorder Division, Indian Institute of Chemical Biology, 4, Raja S.C. Mullik Road, Jadavpur, Kolkata, 700032 India.
Asish K MukhopadhyayNational Institute of Cholera and Enteric Diseases, Kolkata, India.
Snehasikta SwarnakarCancer Biology and Inflammatory Disorder Division, Indian Institute of Chemical Biology, 4, Raja S.C. Mullik Road, Jadavpur, Kolkata, 700032 India.
Indian Institute of Chemical Biology · INNational Institute of Cholera and Enteric Diseases · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

resultsMice infected with AM1/SS1 strain exhibited less gastric inflammation and reduced proMMP9 and proMMP3 activities in gastric tissues as compared to SS1/SS1 and SS1/AM1 infected groups. The expression of both MMP9 and MMP3 followed similar trend like activity in infected tissues. Both Th1 and Th17 responses were induced by SS1 strain more profoundly than AM1 strain infection which induced solely Th1 response in spleen and gastric tissues. Moreover, IFN-γ, TNF-α, IL-1β and IL-12 were significantly downregulated in mice spleen and gastric tissues infected by AM1/SS1 compared to SS1/SS1 but not with SS1/AM1 coinfection. Surprisingly, IL-17 level was dampened significantly in AM1/SS1 compared to SS1/AM1 coinfected groups. Furthermore, number of Foxp3

conclusionsThese data suggested that prior

Indexed as

Cag pathogenicity islandCoinfectionCytokineGastric ulcerHelicobacter pyloriImmunosuppressionInflammationMMP

Identifiers

PMID28286572
PMCPMC5343599
OpenAlexW2592902238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.