Evidence map›Paper›PMID 28286553›Full record

ArticleBiotechnology for biofuels2017

Microbial solvent formation revisited by comparative genome analysis.

Anja Poehlein, José David Montoya Solano, Stefanie K Flitsch, Preben Krabben, Klaus Winzer, Sharon J Reid, David T Jones, Edward Green, Nigel P Minton, Rolf Daniel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Single and multiplexed gene repression in solventogenicSynthetic and systems biotechnology · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Modulation ofFrontiers in genetics · 2022
    Article
  16. Sporulation in solventogenic and acetogenic clostridia.Applied microbiology and biotechnology · 2021
    Review
  17. Frontiers in bioengineering and biotechnology · 2021
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 4 countries.

Anja PoehleinGenomic and Applied Microbiology and Göttingen Genomics Laboratory, Georg-August University Göttingen, Grisebachstr. 8, 37077 Göttingen, Germany.
José David Montoya SolanoInstitut für Mikrobiologie und Biotechnologie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Stefanie K FlitschInstitut für Mikrobiologie und Biotechnologie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.
Preben KrabbenGreen Biologics Ltd., 45A Western Avenue, Milton Park, Abingdon, Oxfordshire OX14 4RU UK.
Klaus WinzerClostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Life Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Sharon J ReidDepartment of Molecular and Cell Biology, University of Cape Town, Rondebosch, Cape Town, 7701 South Africa.
David T JonesDepartment of Microbiology and Immunology, University of Otago, Dunedin, 9010 New Zealand.
Edward GreenCHAIN Biotechnology Ltd., Imperial College Incubator, Level 1 Bessemer Building, Imperial College London, London, SW7 2AZ UK.
Nigel P MintonClostridia Research Group, BBSRC/EPSRC Synthetic Biology Research Centre (SBRC), School of Life Sciences, University of Nottingham, Nottingham, NG7 2RD UK.
Rolf DanielGenomic and Applied Microbiology and Göttingen Genomics Laboratory, Georg-August University Göttingen, Grisebachstr. 8, 37077 Göttingen, Germany.
Peter DürreInstitut für Mikrobiologie und Biotechnologie, Universität Ulm, Albert-Einstein-Allee 11, 89081 Ulm, Germany.ORCID 0000-0002-5586-221X
Universität Ulm · DEEngineering and Physical Sciences Research Council · GBUniversity of Göttingen · DEGreen Biologics (United Kingdom) · GBImperial College London · GBUniversity of Cape Town · ZAUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial formation of acetone, isopropanol, and butanol is largely restricted to bacteria belonging to the genus

resultsThe genomes of a total 30 saccharolytic

conclusionsOur findings represent a comprehensive study of phylogeny and taxonomy of clostridial solvent producers that highlights differences in energy conservation mechanisms and substrate utilization between strains, and allow for the first time a direct comparison of sequentially selected industrial strains at the genetic level. Detailed data mining is now possible, supporting the identification of new engineering targets for improved solvent production.

Indexed as

AcetoneButanolC. beijerinckiiClostridium acetobutylicumC. saccharobutylicumC. saccharoperbutylacetonicumPhylogenySolvents

Identifiers

PMID28286553
PMCPMC5343299
OpenAlexW2592602016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.