Evidence map›Paper›PMID 28285860›Full record

ReviewThe Science of the total environment2017

A discussion about public health, lead and Legionella pneumophila in drinking water supplies in the United States.

Michael B Rosen, Lok R Pokhrel, Mark H Weir

Abstract readReview
In one paragraph

Review in The Science of the total environment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Research gaps and priorities for quantitative microbial risk assessment (QMRA).Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Effects of lead and cadmium on the immune system and cancer progression.Journal of environmental health science & engineering · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Lead-induced changes of cytoskeletal protein is involved in the pathological basis in mice brain.Environmental science and pollution research international · 2018
    Article
  17. Assessment of the Legionnaires' disease outbreak in Flint, Michigan.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michael B RosenDivision of Environmental Health, Department of Epidemiology and Biostatistics, College of Public Health, Temple University, 1301 Cecil B. Moore Avenue, Ritter Annex, Philadelphia, PA 19122, USA.
Lok R PokhrelDivision of Environmental Health, Department of Epidemiology and Biostatistics, College of Public Health, Temple University, 1301 Cecil B. Moore Avenue, Ritter Annex, Philadelphia, PA 19122, USA. Electronic address: tuf80999@temple.edu.
Mark H WeirDivision of Environmental Health Sciences, College of Public Health, The Ohio State University, 426 Cunz Hall, 1841 Neil Ave., Columbus, OH 43210, USA; Department of Civil Environmental and Geodetic Engineering, College of Engineering, The Ohio State University, USA.
Temple University · USThe Ohio State University · US

Funding

QMRA III - Quantitative Microbial Risk Assessment Interdisciplinary InstructionalR25GM108593 · NIGMS · MICHIGAN STATE UNIVERSITY · PI MITCHELL, JADE, WEIR, MARK HOWARD · 2014 to 2018
$792k
NIGMS NIH HHS R25 GM108593
6 · The paper itself

Abstract

Lead (Pb) in public drinking water supplies has garnered much attention since the outset of the Flint water crisis. Pb is a known hazard in multiple environmental matrices, exposure from which results in long-term deleterious health effects in humans. This discussion paper aims to provide a succinct account of environmental Pb exposures with a focus on water Pb levels (WLLs) in the United States. It is understood that there is a strong correlation between WLLs and blood Pb levels (BLLs), and the associated health effects. However, within the Flint water crisis, more than water chemistry and Pb exposure occurred. A cascade of regulatory and bureaucratic failures culminated in the Flint water crisis. This paper will discuss pertinent regulations and responses including their limitations after an overview of the public health effects from Pb exposure as well as discussion on our limitations on monitoring and mitigating Pb in tap water. As the Flint water crisis also included increased Legionnares' disease, caused by Legionella pneumophila, this paper will discuss factors influencing L. pneumophila growth. This will highlight the systemic nature of changes to water chemistry and public health impacts. As we critically analyze these important aspects of water research, we offer discussions to stimulate future water quality research from a new and systemic perspective to inform and guide public health decision-making.

Indexed as

Legionella pneumophilaPublic HealthWater QualityDrinking WaterHumansLeadUnited StatesWater MicrobiologyWater SupplyDrinking WaterLeadBlood lead levelsDrinking waterHealth effectsLeadLegionella pneumophilaRegulations

Identifiers

PMID28285860
PMCPMC6959527
OpenAlexW2592329622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.