ArticleMetabolism: clinical and experimental2017
First and second trimester gestational weight gains are most strongly associated with cord blood levels of hormones at delivery important for glycemic control and somatic growth.
Article in Metabolism: clinical and experimental, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Association of trimester-specific gestational weight gain with child BMI by maternal BMI categories in community-based healthcare organizations.International journal of obesity (2005) · 2026Article
- Early gestational weight gain and birth weight outcome: a Chinese population-based cohort.Pediatric research · 2026Article
- Gestational weight gain patterns as predictors of cesarean deliveries in women diagnosed with gestational diabetes mellitus.BMC pregnancy and childbirth · 2025Article
- Methods for modeling gestational weight gain: empirical application using electronic health record data from a safety net population.BMC pregnancy and childbirth · 2025Article
- Trimester-specific rate of gestational weight loss or gain and birth size: differences by prepregnancy BMI.Obesity (Silver Spring, Md.) · 2024Article
- Gestational weight trajectory and risk of adverse pregnancy outcomes among women with gestational diabetes mellitus: A retrospective cohort study.Maternal & child nutrition · 2024Article
- Recent Insights and Recommendations for Preventing Excessive Gestational Weight Gain.Journal of clinical medicine · 2024Review
- Estimated exposure to perfluoroalkyl substances during infancy and serum-adipokine concentrations in later childhood.Pediatric research · 2023Article
- Gestational Weight Gain Is Associated with the Expression of Genes Involved in Inflammation in Maternal Visceral Adipose Tissue and Offspring Anthropometric Measures.Journal of clinical medicine · 2023Article
- Article
- Hormonal Determinants of Growth and Weight Gain in the Human Fetus and Preterm Infant.Nutrients · 2023Review
- Early Pregnancy Maternal Plasma Phospholipid Saturated Fatty Acids and Fetal Growth: Findings from a Multi-Racial/Ethnic Birth Cohort in US.Nutrients · 2023Article
- Programming of metabolism by adipokines during development.Nature reviews. Endocrinology · 2023Review
- Exposure to maternal fuels during pregnancy and offspring hepatic fat in early childhood: The healthy start study.Pediatric obesity · 2022Article
- Examining the effects of second-and third-trimester gestational weight gain rates on the perinatal outcomes among Chinese twin pregnancies: a retrospective cohort study.BMC pregnancy and childbirth · 2022Article
- The Impact of Gestational Weight Gain on Glucose and Insulin Physiology in Pregnancy-Does Timing Matter?The Journal of clinical endocrinology and metabolism · 2022Article
- Gestational weight gain rates in the first and second trimesters are associated with small for gestational age among underweight women: a prospective birth cohort study.BMC pregnancy and childbirth · 2022Article
- Increased Gestational Weight Gain is Associated with a Higher Risk of Offspring Adiposity Before Five Years of Age: A Population-Based Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Diabetes during Pregnancy: A Maternal Disease Complicating the Course of Pregnancy with Long-Term Deleterious Effects on the Offspring. A Clinical Review.International journal of molecular sciences · 2021Review
- Effect of gestational weight gain on insulin resistance mediated by serum adipokine concentrations in advanced maternal age.Archives of medical science : AMS · 2021Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundExcessive gestational weight gain (GWG) during pregnancy is associated with adverse outcomes for mothers and offspring. Early, mid, and late pregnancy GWGs have different associations with fetal growth and later life adiposity, but associations with cord blood hormones, which might predict later health, are not well studied.
methodsIn 978 pregnant women from the pre-birth Project Viva cohort, we calculated trimester-specific GWG using clinically recorded prenatal weights. Outcomes were levels of umbilical cord blood hormones related to fetal and postnatal growth. We used linear regression models adjusted for maternal race/ethnicity, pre-pregnancy BMI, parity, education, pregnancy smoking status and child sex; 2nd and 3rd trimester models were additionally adjusted for GWG in prior trimesters.
resultsMean±SD pre-pregnancy BMI was 24.9±5.5kg/m
conclusion1st trimester weight gain appears to matter more for cord blood hormones related to offspring glucose/insulin regulation, whereas 2nd trimester gain matters more for hormones related to growth and adiposity.
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