ArticleParasites & vectors2017
The enzootic life-cycle of Borrelia burgdorferi (sensu lato) and tick-borne rickettsiae: an epidemiological study on wild-living small mammals and their ticks from Saxony, Germany.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 50 citations in OpenAlex.
- Identification and mapping of potential and highly likely vectors for selected vector-borne diseases in the EU and neighbouring countries.EFSA journal. European Food Safety Authority · 2026Article
- From reservoirs to ecological integrators: the role of EuropeanFrontiers in veterinary science · 2026Review
- Wild mammals as hosts ofInternational journal for parasitology. Parasites and wildlife · 2025Review
- Effects of host sex, age and behaviour on co-infection patterns in a wild ungulate.Parasitology · 2025Article
- Land use intensity has an impact on Borrelia burgdorferi sensu lato prevalence and genodiversity in ticks from Central Germany.Parasites & vectors · 2025Article
- Influence of tick age and land-use on Borrelia burgdorferi s.l. in Ixodes ricinus ticks from the Swabian Alb, Germany.Parasites & vectors · 2025Article
- Tick-borne zoonotic flaviviruses andOne health (Amsterdam, Netherlands) · 2024Review
- Vector competence of Ixodes ricinus instars for the transmission of Borrelia burgdorferi sensu lato in different small mammalian hosts.Parasites & vectors · 2024Article
- Spotted Fever Group Rickettsiae in Ticks and Small Mammals from Grassland and Forest Habitats in Central Germany.Pathogens (Basel, Switzerland) · 2023Article
- Natural Co-Exposure toLife (Basel, Switzerland) · 2023Article
- Current Data onMicroorganisms · 2022Article
- A Novel High Discriminatory Protocol for the Detection ofPathogens (Basel, Switzerland) · 2022Article
- Diversity of Borrelia burgdorferi sensu lato in ticks and small mammals from different habitats.Parasites & vectors · 2022Article
- Seroprevalence of Borrelia IgG antibodies among individuals from Eastern Slovakia.Central European journal of public health · 2022Article
- The Risk of Exposure to Ticks and Tick-Borne Pathogens in a Spa Town in Northern Poland.Pathogens (Basel, Switzerland) · 2022Article
- An eco-epidemiological modeling approach to investigate dilution effect in two different tick-borne pathosystems.Ecological applications : a publication of the Ecological Society of America · 2022Article
- The Role of Ticks in the Emergence ofMicroorganisms · 2021Review
- Host-parasite interactions of rodent hosts and ectoparasite communities from different habitats in Germany.Parasites & vectors · 2021Article
- Borrelia miyamotoi and Borrelia burgdorferi (sensu lato) identification and survey of tick-borne encephalitis virus in ticks from north-eastern Germany.Parasites & vectors · 2020Article
- Long-term trends of tick-borne pathogens in regard to small mammal and tick populations from Saxony, Germany.Parasites & vectors · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBorrelia burgdorferi (sensu lato) and rickettsiae of the spotted fever group are zoonotic tick-borne pathogens. While small mammals are confirmed reservoirs for certain Borrelia spp., little is known about the reservoirs for tick-borne rickettsiae. Between 2012 and 2014, ticks were collected from the vegetation and small mammals which were trapped in Saxony, Germany. DNA extracted from ticks and the small mammals' skin was analyzed for the presence of Rickettsia spp. and B. burgdorferi (s.l.) by qPCR targeting the gltA and p41 genes, respectively. Partial sequencing of the rickettsial ompB gene and an MLST of B. burgdorferi (s.l.) were conducted for species determination.
resultsIn total, 673 small mammals belonging to eight species (Apodemus agrarius, n = 7; A. flavicollis, n = 214; Microtus arvalis, n = 8; Microtus agrestis, n = 1; Mustela nivalis, n = 2; Myodes glareolus, n = 435; Sorex araneus, n = 5; and Talpa europaea, n = 1) were collected and examined. In total, 916 questing ticks belonging to three species (Ixodes ricinus, n = 741; Dermacentor reticulatus, n = 174; and I. trianguliceps, n = 1) were collected. Of these, 474 ticks were further investigated. The prevalence for Rickettsia spp. and B. burgdorferi (s.l.) in the investigated small mammals was 25.3 and 31.2%, respectively. The chance of encountering Rickettsia spp. in M. glareolus was seven times higher for specimens infested with D. reticulatus than for those which were free of D. reticulatus (OR: 7.0; 95% CI: 3.3-14.7; P < 0.001). In total, 11.4% of questing I. ricinus and 70.5% of D. reticulatus were positive for Rickettsia spp. DNA of B. burgdorferi (s.l.) was detected only in I. ricinus (5.5%). Sequence analysis revealed 9 R. helvetica, 5 R. raoultii, and 1 R. felis obtained from 15 small mammal samples.
conclusionSmall mammals may serve as reservoirs for Rickettsia spp. and B. burgdorferi (s.l.). While the prevalence for Rickettsia spp. in M. glareolus is most likely depending on the abundance of attached D. reticulatus, the prevalence for B. burgdorferi (s.l.) in small mammals is independent of tick abundance. Dermacentor reticulatus may be the main vector of certain Rickettsia spp. but not for Borrelia spp.
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