ArticleParasites & vectors2017
Molecular detection of Hepatozoon spp. and Cytauxzoon sp. in domestic and stray cats from Madrid, Spain.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Who let the cats out? A global meta-analysis on risk of parasitic infection in indoor versus outdoor domestic cats ( Felis catus).Biology letters · 2019Pooled it
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- Prevalence and Sequence Analysis of Vector-Borne Zoonotic Diseases in Stray Cats in Istanbul.Veterinary medicine and science · 2025Article
- Prevalence and genetic characterization of feline leukemia virus in portuguese stray cats.BMC veterinary research · 2025Article
- Hepatozoon spp. in stray cats from the metropolitan area of Rio de Janeiro, Brazil.Parasite (Paris, France) · 2024Article
- Molecular survey on vector-borne pathogens in clinically healthy stray cats in Zaragoza (Spain).Parasites & vectors · 2023Article
- Screening of Domestic Cats from North-Eastern Hungary forPathogens (Basel, Switzerland) · 2023Article
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- Can Domestic Cats Act as Reservoirs ofPathogens (Basel, Switzerland) · 2023Article
- Clinical, diagnostic and epidemiological implications of Hepatozoon spp., Babesia spp. and Leishmania infantum infection in cats and dogs in a Mediterranean periurban setting.Parasitology research · 2023Article
- Molecular survey ofFrontiers in veterinary science · 2023Article
- Ticks, Fleas, and Harboured Pathogens from Dogs and Cats in Cyprus.Pathogens (Basel, Switzerland) · 2022Article
- Molecular detection ofJournal of feline medicine and surgery · 2022Article
- Piroplasmid infection is not associated with clinicopathological and laboratory abnormalities in cats from Midwestern Brazil.Parasitology research · 2022Article
- Piroplasm Infection in Domestic Cats in the Mountainous Region of Rio de Janeiro, Brazil.Pathogens (Basel, Switzerland) · 2022Article
- Molecular epidemiological study on ticks and tick-borne protozoan parasites (Apicomplexa: Cytauxzoon and Hepatozoon spp.) from wild cats (Felis silvestris), Mustelidae and red squirrels (Sciurus vulgaris) in central Europe, Hungary.Parasites & vectors · 2022Article
- Molecular investigation and clinical management of Hepatozoon Canis infection in an Indian jackal - a case report.BMC veterinary research · 2022Article
- First Record ofMicroorganisms · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDifferent species of apicomplexan protozoans of the genera Hepatozoon and Cytauxzoon can infect domestic cats, but their epidemiology and clinical relevance are not fully understood. The aim of this study was to assess the molecular prevalence of Hepatozoon spp. and Cytauxzoon spp. and to identify associated risk factors and clinical and laboratory abnormalities in a population of cats from Madrid, Spain.
methodsSix hundred and forty-four client-owned and stray cats from Madrid, Spain, were included in this study. DNA samples were analyzed by two polymerase chain reaction (PCR) tests to detect a partial sequence of the 18S rRNA gene of Hepatozoon spp. and Cytauxzoon spp. In order to evaluate possible associations between infection by these protozoans and epidemiological or clinical parameters, data were collected related to: the season of sample collection, age, gender, spayed/neutered status, breed, living area, lifestyle, outdoor access, contact with other animals, prey on wild animals, history of tick or flea infestation, travel history, ectoparasiticide treatment, previous blood transfusion, previous tetracycline administration in the last 60 days, Feline Leukemia virus (FeLV) and Feline Immunodeficiency virus (FIV) status, positivity to other vector-borne diseases, the presence or absence of clinical signs and hematological or biochemical alterations.
resultsDNA of Hepatozoon spp. and Cytauxzoon sp. was amplified from the blood of 10 (1.6%) and 8 (1.2%) cats, respectively. Previous treatment with tetracyclines in the last 60 days, previous administration of blood transfusion, a decrease in haematocrit and an increase in creatinine were associated with Hepatozoon spp. infection. Cytauxzoon sp. infection was more frequent in samples collected during the winter months and in cats living in rural areas. This infection was associated with a FIV-positive status. Some of the cats that were positive for Hepatozoon spp. or Cytauxzoon sp. had been exposed to other vector-borne pathogens, such as Ehrlichia canis and Bartonella henselae.
conclusionsOur results indicate that cats from Madrid, central Spain, are infected with Hepatozoon spp. and Cytauxzoon sp., although with a low prevalence. Further studies are needed to determine the virulence of these agents in Spanish cats.
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