ArticleParasites & vectors2017
Serological association between Leishmania infantum and sand fly fever Sicilian (but not Toscana) virus in sheltered dogs from southern Portugal.
Article in Parasites & vectors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Canine Leishmaniasis in Europe over the Last Decade: A Review of Geographic Trends and Epidemiological Data.Pathogens (Basel, Switzerland) · 2025Pooled it
- Article
- Catching up with old friends: a 2-year survey of phlebotomine sand fly-borne phleboviruses presence in southern Portugal.Parasites & vectors · 2026Article
- Seroprevalence of sand fly fever Sicilian virus in blood donors in mainland Portugal.Parasites & vectors · 2025Article
- Seroprevalence of Toscana virus in blood donors in mainland Portugal.Parasites & vectors · 2025Article
- Toscana virus - an emerging Mediterranean arbovirus transmitted by sand flies.The Journal of general virology · 2024Review
- Toscana Virus in Wild-Caught Sand Flies in Portugal, Findings from the National Vector Surveillance Network, 2023.Pathogens (Basel, Switzerland) · 2024Article
- Global Distribution of Canine Visceral Leishmaniasis and the Role of the Dog in the Epidemiology of the Disease.Pathogens (Basel, Switzerland) · 2024Review
- Co-Circulation ofTropical medicine and infectious disease · 2023Article
- Retrospective Analysis of Leishmaniasis in Sicily (Italy) from 2013 to 2021: One-Health Impact and Future Control Strategies.Microorganisms · 2022Article
- Review
- Human seroprevalence of Toscana virus and Sicilian phlebovirus in the southwest of Portugal.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- Seroprevalence and risk factors associated with exposure to Leishmania infantum in dogs, in an endemic Mediterranean region.PloS one · 2021Article
- Monitoring Leishmania infection and exposure to Phlebotomus perniciosus using minimal and non-invasive canine samples.Parasites & vectors · 2020Article
- Experimental Infection of Dogs with Toscana Virus and Sandfly Fever Sicilian Virus to Determine Their Potential as Possible Vertebrate Hosts.Microorganisms · 2020Article
- Broader Geographical Distribution of Toscana Virus in the Mediterranean Region Suggests the Existence of Larger Varieties of Sand Fly Vectors.Microorganisms · 2020Article
- Antibody Response to Toscana Virus and Sandfly Fever Sicilian Virus in Cats Naturally Exposed to Phlebotomine Sand Fly Bites in Portugal.Microorganisms · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhlebotomine sand fly-borne diseases such as leishmanioses and phleboviruses are emerging threats to animal and public health. Canine leishmaniosis caused by Leishmania infantum is an endemic zoonosis in Portugal. Antibodies to Toscana virus (TOSV) and sand fly fever Sicilian virus (SFSV) were also reported in dogs from the south of the country. The aim of this work was to evaluate a possible association between exposure to L. infantum, TOSV and SFSV in sheltered dogs from the south of Portugal.
resultsSeventy-six (13.1%) out of 581 dogs were seropositive for L. infantum, 327 (56.3%) for SFSV and 36 (6.2%) for TOSV. Six dogs were co-exposed with L. infantum and TOSV, 51 with L. infantum and SFSV and 25 with TOSV and SFSV. One dog had antibodies to the three pathogens. Leishmania infantum seroprevalence was significantly higher in pure breed dogs than in mongrels and in dogs with clinical signs while SFSV positivity was significantly higher in males, in pure and cross-breed dogs than in mongrels and in those not treated with insecticides. Seroprevalence for both viruses was significantly higher in dogs over than 7 years-old than in those aged 1-7. A significant association was observed between the presence of antibodies to L. infantum and SFSV.
conclusionsThe presence of antibodies to several phlebotomine sand fly-borne pathogens in dogs, reinforces the need to implement efficient prophylactic measures to prevent infection among vertebrate hosts including humans. The results also indicate that dogs are good sentinels for assessing human exposure to TOSV and SFSV. Further studies must be performed to elucidate the role of dogs in the dynamics of transmission and if they can play a role as amplifying or reservoir hosts in the natural cycle of these viruses. Public and animal health impacts of these phleboviruses in Portugal should be addressed via serological and virological studies on both phlebotomine sand flies and vertebrate hosts, especially on humans.
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