Evidence map›Paper›PMID 28285362›Full record

ArticleMolecular and cellular biochemistry2017

Purinergic ecto-enzymes participate in the thromboregulation in acute in mice infection by Trypanosoma cruzi.

Guilherme M do Carmo, Pedro H Doleski, Mariângela F de Sá, Thirssa H Grando, Nathieli B Bottari, Daniela B R Leal, Lucas T Gressler, Ricardo E Mendes, Lenita M Stefani, Silvia G Monteiro and 1 more

Open access · greenAbstract read
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In one paragraph

Article in Molecular and cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Guilherme M do CarmoDepartment of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil.
Pedro H DoleskiDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Mariângela F de SáDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Thirssa H GrandoDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Nathieli B BottariDepartment of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil.
Daniela B R LealDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Lucas T GresslerDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Ricardo E MendesVeterinary Pathology Laboratory, Instituto Federal Catarinense (IFC), Concórdia, Brazil.
Lenita M StefaniDepartment of Animal Science, Universidade do Estado de Santa Catarina (UDESC), Chapecó, Brazil.
Silvia G MonteiroDepartment of Microbiology and Parasitology, Universidade Federal de Santa Maria (UFSM), Santa Maria, RS, Brazil.
Aleksandro S Da SilvaDepartment of Biochemistry and Molecular Biology, Universidade Federal de Santa Maria (UFSM), Santa Maria, Brazil. aleksandro_ss@yahoo.com.br.
Universidade Federal de Santa Maria · BRUniversidade do Estado de Santa Catarina · BRInstituto Federal Catarinense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coagulation disorders have been described in Chagas disease with thrombocytopenia as an important event. Several mechanisms may be related to this pathogenesis, such as enzymes of the purinergic system, purine, and receptors involved in the regulation and modulation of physiological events related to hemostasis. Therefore, the aim of this study was to evaluate the activities of E-NTPDase, E-5'nucleotidase, and ecto-adenosine deaminase (E-ADA) in platelets of mice experimentally infected by Trypanosoma cruzi. Twelve female mice were used, divided into two groups (n = 6): uninfected and infected. Mice of infected group were intraperitoneally inoculated with 10

Indexed as

Adenosine DeaminaseAdenosine TriphosphateAnimalsBlood PlateletsChagas DiseaseFemaleMiceProtozoan ProteinsThrombocytopeniaTrypanosoma cruziAdenosine DeaminaseAdenosine TriphosphateProtozoan ProteinsChagas diseaseCoagulation disordersPurinergic ecto-enzymes

Identifiers

PMID28285362
OpenAlexW2594362702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.