Evidence map›Paper›PMID 28285208›Full record

ArticleAddictive behaviors2017

Predictors of tobacco abstinence in outpatient smokers with schizophrenia or bipolar disorder treated with varenicline and cognitive behavioral smoking cessation therapy.

Randi M Schuster, Corinne Cather, Gladys N Pachas, Haiyue Zhang, Kristina M Cieslak, Susanne S Hoeppner, David Schoenfeld, A Eden Evins

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Addictive behaviors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Randi M SchusterCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States.
Corinne CatherCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States. Electronic address: ccather@mgh.harvard.edu.
Gladys N PachasCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States.
Haiyue ZhangCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; MGH Biostatistics Center, United States; Harvard T.H. Chan School of Public Health, United States.
Kristina M CieslakCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States.
Susanne S HoeppnerCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States.
David SchoenfeldHarvard Medical School, United States; MGH Biostatistics Center, United States; Harvard T.H. Chan School of Public Health, United States.
A Eden EvinsCenter for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, United States; Harvard Medical School, United States.
Harvard University · USMassachusetts General Hospital · US

Funding

Smoking Cessation and Smoking Relapse Prevention in Patients with SchizophreniaR01DA021245 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI EVINS, A EDEN · 2007 to 2010
$3.1M
Fostering Research Mentorship & Training during Psychiatry Residency SupplementR25MH094612 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI FAVA, MAURIZIO, GREENFIELD, SHELLY F. · 2011 to 2022
$2.3M
Mentoring in Addiction Treatment ResearchK24DA030443 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI EVINS, A EDEN · 2010 to 2020
$2.0M
NIDA NIH HHS K24 DA030443NIDA NIH HHS R01 DA021245NIMH NIH HHS R25 MH094612
6 · The paper itself

Abstract

backgroundThe estimated mortality gap between those with and without serious mental illness (SMI) is increasing, now estimated at 28years, which is largely due to smoking-related diseases.

aimsWe sought to identify predictors of 14-day continuous abstinence in stable outpatient smokers with SMI.

methodAdult smokers with schizophrenia spectrum (n=130) or bipolar disorder (n=23) were enrolled in a 12-week course of varenicline and cognitive-behavioral therapy for smoking cessation.

resultsIndependent predictors of abstinence included reduction in withdrawal symptoms prior to the quit day, fewer cigarettes smoked per day at baseline, better baseline attention, remitted alcohol dependence, and lower expectation of peer support to aid quitting.

conclusionsInterventions that consider these targets may improve smoking cessation outcomes in those with SMI.

Indexed as

Cognitive Behavioral TherapyAttentionBipolar DisorderComorbidityFemaleHumansMaleMiddle AgedNicotinic AgonistsOutpatientsSchizophreniaSmokersSmoking CessationSubstance Withdrawal SyndromeTobacco Use DisorderVareniclineNicotinic AgonistsVareniclineAbstinenceBipolarNicotinePredictorsSchizophreniaSmoking cessationVarenicline

Identifiers

PMID28285208
PMCPMC6499932
OpenAlexW2590989604

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.