Evidence map›Paper›PMID 28284670›Full record

ReviewTranslational research : the journal of laboratory and clinical medicine2017

Vascular precursor cells in tissue injury repair.

Xin Shi, Weihong Zhang, Liya Yin, William M Chilian, Jessica Krieger, Ping Zhang

Abstract readReview
In one paragraph

Review in Translational research : the journal of laboratory and clinical medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Identification of CD141Stem cell research & therapy · 2024
    Article
  7. Dynamics of Gill Responses to a Natural Infection withAnimals : an open access journal from MDPI · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Fli-1 Governs Pericyte Dysfunction in a Murine Model of Sepsis.The Journal of infectious diseases · 2018
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xin ShiDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio.
Weihong ZhangDepartment of Basic Medicine, School of Nursing, Zhengzhou University, Zhengzhou, Henan Province, PR China.
Liya YinDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio.
William M ChilianDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio.
Jessica KriegerDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio.
Ping ZhangDepartment of Integrative Medical Sciences, College of Medicine, Northeast Ohio Medical University, Rootstown, Ohio. Electronic address: pzhang@neomed.edu.
Northeast Ohio Medical University · USZhengzhou University · CN

Funding

Regulation of Lipid and Lipoprotein Metabolism by Nuclear ReceptorsR01HL103227 · NHLBI · NORTHEAST OHIO MEDICAL UNIVERSITY · PI YIN, LIYA, ZHANG, YANQIAO · 2011 to 2019
$3.1M
Alcohol, Septicemia and the LKS Cell ResponseR01AA019676 · NIAAA · NORTHEAST OHIO MEDICAL UNIVERSITY · PI ZHANG, PING · 2010 to 2014
$1.7M
Alcohol, hedgehog signal, and HSC dysfunction in host defense against septicemiaR01AA022816 · NIAAA · NORTHEAST OHIO MEDICAL UNIVERSITY · PI ZHANG, PING · 2014 to 2018
$1.7M
NHLBI NIH HHS R01 HL103227NIAAA NIH HHS R01 AA019676NIAAA NIH HHS R01 AA022816
6 · The paper itself

Abstract

Vascular precursor cells include stem cells and progenitor cells giving rise to all mature cell types in the wall of blood vessels. When tissue injury occurs, local hypoxia and inflammation result in the generation of vasculogenic mediators which orchestrate migration of vascular precursor cells from their niche environment to the site of tissue injury. The intricate crosstalk among signaling pathways coordinates vascular precursor cell proliferation and differentiation during neovascularization. Establishment of normal blood perfusion plays an essential role in the effective repair of the injured tissue. In recent years, studies on molecular mechanisms underlying the regulation of vascular precursor cell function have achieved substantial progress, which promotes exploration of vascular precursor cell-based approaches to treat chronic wounds and ischemic diseases in vital organ systems. Verification of safety and establishment of specific guidelines for the clinical application of vascular precursor cell-based therapy remain major challenges in the field.

Indexed as

Wound HealingAnimalsCell DifferentiationCell ProliferationEndothelium, VascularHumansNeovascularization, PhysiologicRegenerationStem Cells

Identifiers

PMID28284670
PMCPMC5429880
OpenAlexW2591000278

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.