Evidence map›Paper›PMID 28283888›Full record

ArticleMolecular neurobiology2018

Kinin Receptors Sensitize TRPV4 Channel and Induce Mechanical Hyperalgesia: Relevance to Paclitaxel-Induced Peripheral Neuropathy in Mice.

Robson Costa, Maíra A Bicca, Marianne N Manjavachi, Gabriela C Segat, Fabiana Chaves Dias, Elizabeth S Fernandes, João B Calixto

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Kinin BPharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Kinin BPharmaceutics · 2023
    Article
  8. Kinin BPharmaceutics · 2023
    Article
  9. TRPV4 Role in Neuropathic Pain Mechanisms in Rodents.Antioxidants (Basel, Switzerland) · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Robson CostaDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil.
Maíra A BiccaDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil.
Marianne N ManjavachiDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil.
Gabriela C SegatDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil.
Fabiana Chaves DiasPrograma de Pós-graduação de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Elizabeth S FernandesPrograma de Pós-Graduação em Biologia Parasitária, Universidade Ceuma, São Luís, MA, Brazil.
João B CalixtoDepartamento de Farmacologia, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, Florianópolis, SC, 88049-900, Brazil. calixto@farmaco.ufsc.br.
Universidade Federal de Santa Catarina · BRUniversidade Federal do Rio de Janeiro · BRKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kinin B

Indexed as

AnimalsBradykininBradykinin B2 Receptor AntagonistsHyperalgesiaMaleMicePaclitaxelPeripheral Nervous System DiseasesPhysical StimulationReceptor, Bradykinin B1Receptor, Bradykinin B2TRPV Cation ChannelsTubulin ModulatorsBradykininBradykinin B2 Receptor Antagonistsbradykinin, Leu(8)-des-Arg(9)-icatibantPaclitaxelReceptor, Bradykinin B1Receptor, Bradykinin B2Trpv4 protein, mouseTRPV Cation ChannelsTubulin ModulatorsKininsNeuropathic painPaclitaxelPeripheral neuropathyTRPV4

Identifiers

PMID28283888
OpenAlexW2592976233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.