Evidence map›Paper›PMID 28283769›Full record

ReviewDer Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft2017

[In vivo imaging of the corneal nerve plexus : From single image to large scale map].

B Köhler, S Allgeier, A Bartschat, R F Guthoff, S Bohn, K-M Reichert, O Stachs, K Winter, R Mikut

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

B KöhlerInstitut für Angewandte Informatik, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131, Karlsruhe, Deutschland. bernd.koehler@kit.edu.
S AllgeierInstitut für Angewandte Informatik, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131, Karlsruhe, Deutschland.
A BartschatInstitut für Angewandte Informatik, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131, Karlsruhe, Deutschland.
R F GuthoffUniversitätsaugenklinik, Universitätsmedizin Rostock, Rostock, Deutschland.
S BohnUniversitätsaugenklinik, Universitätsmedizin Rostock, Rostock, Deutschland.
K-M ReichertInstitut für Angewandte Informatik, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131, Karlsruhe, Deutschland.
O StachsUniversitätsaugenklinik, Universitätsmedizin Rostock, Rostock, Deutschland.
K WinterInstitut für Anatomie, Medizinische Fakultät, Universität Leipzig, Leipzig, Deutschland.
R MikutInstitut für Angewandte Informatik, Karlsruher Institut für Technologie, Kaiserstraße 12, 76131, Karlsruhe, Deutschland.
Karlsruhe Institute of Technology · DEUniversitätsmedizin Rostock · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sub-basal nerve plexus (SNP) of the cornea provides the possibility of in vivo and non-invasive examination of peripheral nerve structures by corneal confocal microscopy (CCM). Thus morphological alterations of the SNP can be directly detected and quantified. A single CCM image is insufficient for a well-founded diagnosis because of the inhomogeneous distribution of the nerve fibers; therefore, there is a demand for techniques for large area imaging of the SNP. This article provides an overview of published approaches to the problem. Current developmental work at the Karlsruhe Institute of Technology and the University of Rostock Eye Clinic is expected to lead to a simplified handling of the technology and a further improvement in the image quality.

Indexed as

CorneaEarly DiagnosisEye MovementsHumansImage Interpretation, Computer-AssistedIntravital MicroscopyMicroscopy, ConfocalNerve FibersPeripheral Nervous System DiseasesSoftwareConfocal microscopyEye movementImage processingMosaic imagesNerve fibers

Identifiers

PMID28283769
OpenAlexW2593417618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.