Evidence map›Paper›PMID 28283561›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.

Gregg W Crabtree, Ziyi Sun, Mirna Kvajo, Jantine A C Broek, Karine Fénelon, Heather McKellar, Lan Xiao, Bin Xu, Sabine Bahn, James M O'Donnell and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

  1. Pooled it
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  13. The computational power of the human brain.Frontiers in cellular neuroscience · 2023
    Review
  14. Article
  15. eLife · 2022
    Article
  16. An in vitro model of neuronal ensembles.Nature communications · 2022
    Article
  17. Article
  18. Article
  19. Neuronal oscillations: early biomarkers of psychiatric disease?Frontiers in behavioral neuroscience · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Gregg W CrabtreeDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, and.
Ziyi SunDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, and.
Mirna KvajoDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, and.
Jantine A C BroekCambridge Centre for Neuropsychiatric Research, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, United Kingdom.
Karine FénelonDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, and.
Heather McKellarIntegrated Program in Cellular, Molecular, and Biophysical Studies, Columbia University, New York, New York 10032.
Lan XiaoFlorida State University School of Medicine, Tallahassee, Florida 32304.
Bin XuDepartments of Psychiatry and.
Sabine BahnCambridge Centre for Neuropsychiatric Research, Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, United Kingdom.
James M O'DonnellSchool of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York 14214.ORCID 0000-0002-8994-7588
Joseph A GogosDepartment of Physiology and Cellular Biophysics, College of Physicians and Surgeons, and jag90@cumc.columbia.edu.
Columbia College · CAUniversity of Cambridge · GBColumbia University · USColumbia University Irving Medical Center · USFlorida State University · USUniversity at Buffalo, State University of New York · US

Funding

Elucidating the Effect of Disc 1 on Neurodevelopment and Synaptic TransmissionR01MH080234 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GOGOS, JOSEPH A · 2007 to 2016
$3.3M
Integrative methods for the identification of causal variants in mental disorderR01MH106910 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI IONITA, IULIANA, XU, BIN · 2016 to 2018
$1.2M
NIMH NIH HHS R01 MH080234NIMH NIH HHS R01 MH106910
6 · The paper itself

Abstract

Using a genetic mouse model that faithfully recapitulates a

Indexed as

Disease Models, AnimalAction PotentialsAnimalsFemaleMaleMiceMice, Inbred C57BLMice, TransgenicNerve Tissue ProteinsNeuronal PlasticityNeuronsPrefrontal CortexPregnancySchizophreniaDisc1 protein, mouseNerve Tissue ProteinsDisc1 mouse modelexcitabilityKv channelsprefrontal cortexschizophreniasynaptic plasticity

Identifiers

PMID28283561
PMCPMC5391686
OpenAlexW2591737845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.