ArticlePharmaceutical biology2017
Quantitative analysis of rutin, quercetin, naringenin, and gallic acid by validated RP- and NP-HPTLC methods for quality control of anti-HBV active extract of Guiera senegalensis.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 62 citations in OpenAlex.
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- Quercetin and its derivates as antiviral potentials: A comprehensive review.Phytotherapy research : PTR · 2022Review
- Novel Anti-Hepatitis B Virus Activity ofACS omega · 2021Article
- Therapeutic potential of phytoconstituents of edible fruits in combating emerging viral infections.Journal of food biochemistry · 2021Review
- Electrochemical determination of rutin by using NiFeJournal of materials science. Materials in electronics · 2021Article
- Naringenin, a flavanone with antiviral and anti-inflammatory effects: A promising treatment strategy against COVID-19.Phytotherapy research : PTR · 2020Review
- Review
- Bioassay-guided isolation of anti-hepatitis B virus flavonoid myricetin-3-Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- A High Performance Thin Layer Chromatographic Method Using a Design of Experiment Approach for Estimation of Phytochemicals in Extracts ofTurkish journal of pharmaceutical sciences · 2020Article
- Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action.Frontiers in immunology · 2020Review
- Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2019Article
- Protective effect ofExperimental and therapeutic medicine · 2018Article
- Molecular Structure-Affinity Relationship of Flavonoids in Lotus Leaf (Nelumbo nucifera Gaertn.) on Binding to Human Serum Albumin and Bovine Serum Albumin by Spectroscopic Method.Molecules (Basel, Switzerland) · 2017Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextGuiera senegalensis J.F. Gmel (Combretaceae) is a folk medicinal plant used in various metabolic and infectious diseases. In addition to its antiviral activities against herpes and fowlpox, the anti-HBV efficacy is very recently reported.
objectiveTo develop and validate simple, sensitive RP-/NP-HPTLC methods for quantitative determination of biomarkers rutin, quercetin, naringenin, and gallic acid in the anti-HBV active G. senegalensis leaves ethanol-extract. MATERIALS AND
methodsRP-HPTLC (rutin & quercetin; phase- acetonitrile:water, 4:6) and NP-HPTLC (naringenin & gallic acid; phase- toluene:ethyl acetate:formic acid, 6:4:0.8) were performed on glass-backed silica gel plates 60F
resultsWell-separated and compact spots (R
conclusionThe validated NP-/RP-HPTLC methods were simple, accurate, and sensitive for separating and quantifying antiviral biomarkers in G. senegalensis, and endorsed its anti-HBV activity. The developed methods could be further employed in the standardization and quality-control of herbal formulations.
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