Evidence map›Paper›PMID 28282876›Full record

ArticleInternational journal of molecular sciences2017

Hepatic Transcriptome Profiles of Mice with Diet-Induced Nonalcoholic Steatohepatitis Treated with Astaxanthin and Vitamin E.

Masuko Kobori, Yumiko Takahashi, Mutsumi Sakurai, Yinhua Ni, Guanliang Chen, Mayumi Nagashimada, Shuichi Kaneko, Tsuguhito Ota

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Effects ofAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Article
  4. Article
  5. Review
  6. Preventative and Therapeutic Effects of Astaxanthin on NAFLD.Antioxidants (Basel, Switzerland) · 2023
    Review
  7. Review
  8. Article
  9. Astaxanthin FromFrontiers in nutrition · 2022
    Article
  10. Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2020
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Masuko KoboriFood Research Institute, National Agriculture and Food Resrach Organization, Tsukuba, Ibaraki 305-8642, Japan. kobori@affrc.go.jp.
Yumiko TakahashiFood Research Institute, National Agriculture and Food Resrach Organization, Tsukuba, Ibaraki 305-8642, Japan. yumitala@affrc.go.jp.
Mutsumi SakuraiFood Research Institute, National Agriculture and Food Resrach Organization, Tsukuba, Ibaraki 305-8642, Japan. imustum@affrc.go.jp.
Yinhua NiDepartment of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. shali0145@gmail.com.
Guanliang ChenDepartment of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. guanliangc@gmail.com.
Mayumi NagashimadaDepartment of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. nakanaga@staff.kanazawa-u.ac.jp.
Shuichi KanekoDepartment of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. skaneko@m-kanazawa.jp.
Tsuguhito OtaDepartment of Cell Metabolism and Nutrition, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8640, Japan. tota@staff.kanazawa-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Astaxanthin alleviates hepatic lipid accumulation and peroxidation, inflammation, and fibrosis in mice with high-cholesterol, high-cholate, and high-fat (CL) diet-induced nonalcoholic steatohepatitis (NASH) [...].

Indexed as

TranscriptomeAnimalsDiet, High-FatDisease Models, AnimalEukaryotic Initiation Factor-2Gene Expression ProfilingLiverMaleMiceMitochondriaNon-alcoholic Fatty Liver DiseasePPAR alphaPPAR deltaProtein Interaction MappingProtein Interaction MapsRetinoic Acid Receptor alphaastaxanthineEukaryotic Initiation Factor-2PPAR alphaPPAR deltaRetinoic Acid Receptor alphaVitamin EXanthophyllsastaxanthincomprehensive gene expression analysiseukaryotic initiation factor-2 (EIF2)nonalcoholic steatohepatitis (NASH)peroxisome proliferator-activated receptor α (PPARA)vitamin E

Identifiers

PMID28282876
PMCPMC5372609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.