ArticleJournal of Parkinson's disease2017
My 25 Stimulating Years with DBS in Parkinson's Disease.
Article in Journal of Parkinson's disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Remote Regulation of Molecular Diffusion in Extracellular Space of Parkinson's Disease Rat Model by Subthalamic Nucleus Deep Brain Stimulation.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Fractal Electronics for Stimulating and Sensing Neural Networks: Enhanced Electrical, Optical, and Cell Interaction Properties.Advances in neurobiology · 2024Article
- Deep-Brain Subthalamic Nucleus Stimulation Enhances Food-Related Motivation by Influencing Neuroinflammation and Anxiety Levels in a Rat Model of Early-Stage Parkinson's Disease.International journal of molecular sciences · 2023Article
- Article
- Anthropology of Deep Brain Stimulation; the 30th Anniversary of STN DBS in 2023.Movement disorders clinical practice · 2023Review
- Deep Brain Stimulation: Emerging Tools for Simulation, Data Analysis, and Visualization.Frontiers in neuroscience · 2022Review
- A Functional Connectome of Parkinson's Disease Patients Prior to Deep Brain Stimulation: A Tool for Disease-Specific Connectivity Analyses.Frontiers in neuroscience · 2022Article
- Article
- Treatment Options for Motor and Non-Motor Symptoms of Parkinson's Disease.Biomolecules · 2021Review
- Patient, Caregiver, and Decliner Perspectives on Whether to Enroll in Adaptive Deep Brain Stimulation Research.Frontiers in neuroscience · 2021Article
- Review
- Article
- Anatomical brain structures normalization for deep brain stimulation in movement disorders.NeuroImage. Clinical · 2020Article
- An update on best practice of deep brain stimulation in Parkinson's disease.Therapeutic advances in neurological disorders · 2019Review
- Understanding the Effects and Adverse Reactions of Deep Brain Stimulation: Is It Time for a Paradigm Shift Toward a Focus on Heterogenous Biophysical Tissue Properties Instead of Electrode Design Only?Frontiers in human neuroscience · 2018Article
- The MPTP Story.Journal of Parkinson's disease · 2017Review
- Bringing Advanced Therapies for Parkinson's Disease to the Clinic: The Patient's Perspective.Journal of Parkinson's diseaseReview
- The Times They Are a-Changin': Parkinson's Disease 20 Years from Now.Journal of Parkinson's diseaseArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The year 2017 marks the 30th anniversary of the birth of modern deep brain stimulation (DBS), which was introduced by Benabid, Pollak et al. in 1987, initially targeting the motor thalamus to treat tremor, and subsequently targeting the subthalamic nucleus (STN) for treatment of symptoms of advanced Parkinson's disease (PD). STN DBS is undoubtedly "the most important discovery since levodopa", as stated by David Marsden in 1994. In 2014, The Lasker- DeBakey Clinical Medical Research Award to "honor two scientists who developed deep brain stimulation of the subthalamic nucleus", was bestowed upon Benabid and DeLong. STN DBS remains today the main surgical procedure for PD, due to its effectiveness in ameliorating PD symptoms and because it is the only surgical procedure for PD that allows a radical decrease in medication. Future improvements of DBS include the possibility to deliver a "closed-loop", "on demand" stimulation, as highly preliminary studies suggest that it may improve both axial and appendicular symptoms and reduce side effects such as dysarthria. Even though DBS of the subthalamic nucleus is the main surgical procedure used today for patients with PD, all patients are not suitable for STN DBS; as a functional neurosurgeon performing since more than 25 years various surgical procedures the aim of which is not to save life but to improve the patient's quality of life, I consider that the surgery should be tailored to the patient's individual symptoms and needs, and that its safety is paramount.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.