Evidence map›Paper›PMID 28282456›Full record

ArticlePloS one2017

Early computed tomography-based scores to predict decompressive hemicraniectomy after endovascular therapy in acute ischemic stroke.

Ilko L Maier, Daniel Behme, Marlena Schnieder, Ioannis Tsogkas, Katharina Schregel, Mathias Bähr, Michael Knauth, Jan Liman, Marios-Nikos Psychogios

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ilko L MaierDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.ORCID http://orcid.org/0000-0001-6988-8878
Daniel BehmeDepartment of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Marlena SchniederDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.
Ioannis TsogkasDepartment of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Katharina SchregelDepartment of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Mathias BährDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.
Michael KnauthDepartment of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
Jan LimanDepartment of Neurology, University Medical Center Goettingen, Goettingen, Germany.
Marios-Nikos PsychogiosDepartment of Neuroradiology, University Medical Center Goettingen, Goettingen, Germany.
University of Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdentification of patients requiring decompressive hemicraniectomy (DH) after endovascular therapy (EVT) is crucial as clinical signs are not reliable and early DH has been shown to improve clinical outcome. The aim of our study was to identify imaging-based scores to predict the risk for space occupying ischemic stroke and DH.

methodsProspectively derived data from patients with acute large artery occlusion within the anterior circulation and EVT was analyzed in this monocentric study. Predictive value of non-contrast cranial computed tomography (ncCT) and cerebral blood volume (CBV) Alberta Stroke Program Early CT score (ASPECTS) were investigated for DH using logistic regression models and Receiver Operating Characteristic Curve analysis.

resultsFrom 218 patients with EVT, DH was performed in 20 patients (9.2%). Baseline- (7 vs. 9; p = 0.009) and follow-up ncCT ASPECTS (1 vs. 7, p<0.001) as well as baseline CBV ASPECTS (5 vs. 7, p<0.001) were significantly lower in patients with DH. ncCT (baseline: OR 0.71, p = 0.018; follow-up: OR 0.32, p = <0.001) and CBV ASPECTS (OR 0.63, p = 0.008) predicted DH. Cut-off ncCT-ASPECTS on baseline was 7-, ncCT-ASPECTS on follow-up was 4- and CBV ASPECTS on baseline was 5 points.

conclusionsASPECTS could be useful to early identify patients requiring DH after EVT for acute large vessel occlusion.

Indexed as

Decompressive CraniectomyAgedBrain IschemiaCerebral Blood VolumeEndovascular ProceduresFemaleHumansLogistic ModelsMaleMiddle AgedProspective StudiesROC CurveStrokeTomography, X-Ray Computed

Identifiers

PMID28282456
PMCPMC5345861
OpenAlexW2594058015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.