ArticlePloS one2017
Coevolution with bacteria drives the evolution of aerobic fermentation in Lachancea kluyveri.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Gut yeasts accelerate chill coma recovery in Drosophila melanogaster.The Journal of experimental biology · 2026Article
- Mitochondrial ATP generation is more proteome efficient than glycolysis.Nature chemical biology · 2024Article
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
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- Enforced Mutualism Leads to Improved Cooperative Behavior betweenMicroorganisms · 2020Article
- Performance, genomic rearrangements, and signatures of adaptive evolution: Lessons from fermentative yeasts.Ecology and evolution · 2020Article
- Evolution of mutualistic behaviour between Chlorella sorokiniana and Saccharomyces cerevisiae within a synthetic environment.Journal of industrial microbiology & biotechnology · 2020Article
- Ethanol-Enriched Substrate Facilitates Ambrosia Beetle Fungi, but Inhibits Their Pathogens and Fungal Symbionts of Bark Beetles.Frontiers in microbiology · 2020Article
- Assembly and Analysis of the Genome Sequence of the YeastMicroorganisms · 2019Article
- Improvement of thermotolerance in Lachancea thermotolerans using a bacterial selection pressure.Journal of industrial microbiology & biotechnology · 2019Article
- Symbiont selection via alcohol benefits fungus farming by ambrosia beetles.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Genome dynamics and evolution in yeasts: A long-term yeast-bacteria competition experiment.PloS one · 2018Article
- Survival and Energy Producing Strategies of Alkane Degraders Under Extreme Conditions and Their Biotechnological Potential.Frontiers in microbiology · 2018Review
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Authors and funding
7 authors.
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Abstract
The Crabtree positive yeasts, such as Saccharomyces cerevisiae, prefer fermentation to respiration, even under fully aerobic conditions. The selective pressures that drove the evolution of this trait remain controversial because of the low ATP yield of fermentation compared to respiration. Here we propagate experimental populations of the weak-Crabtree yeast Lachancea kluyveri, in competitive co-culture with bacteria. We find that L. kluyveri adapts by producing quantities of ethanol lethal to bacteria and evolves several of the defining characteristics of Crabtree positive yeasts. We use precise quantitative analysis to show that the rate advantage of fermentation over aerobic respiration is insufficient to provide an overall growth advantage. Thus, the rapid consumption of glucose and the utilization of ethanol are essential for the success of the aerobic fermentation strategy. These results corroborate that selection derived from competition with bacteria could have provided the impetus for the evolution of the Crabtree positive trait.
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