Evidence map›Paper›PMID 28282151›Full record

ArticleJournal of proteome research2017

Quantitative Proteomic Analysis of Human Airway Cilia Identifies Previously Uncharacterized Proteins of High Abundance.

Kevin Blackburn, Ximena Bustamante-Marin, Weining Yin, Michael B Goshe, Lawrence E Ostrowski

Abstract read
In one paragraph

Article in Journal of proteome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Molecular basis for the activation of outer dynein arms in cilia.Nature structural & molecular biology · 2025
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  11. The methylome of motile cilia.Molecular biology of the cell · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kevin BlackburnDepartment of Molecular and Structural Biochemistry, North Carolina State University , Raleigh, North Carolina 27695, United States.
Ximena Bustamante-MarinMarsico Lung Institute/UNC CF Research Center, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
Weining YinMarsico Lung Institute/UNC CF Research Center, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
Michael B GosheDepartment of Molecular and Structural Biochemistry, North Carolina State University , Raleigh, North Carolina 27695, United States.
Lawrence E OstrowskiMarsico Lung Institute/UNC CF Research Center, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.ORCID 0000-0002-7558-6603
University of North Carolina at Chapel Hill · USNorth Carolina State University · US

Funding

Vector CoreP30DK065988 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Richard Charles Boucher, Martina Gentzsch · 2004 to 2026
$26.5M
Longitudinal Characterization of Respiratory Tract Exacerbations and Treatment Responses in Primary Ciliary DyskinesiaU54HL096458 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DELL, SHARON · 2009 to 2023
$20.0M
Pathogenesis of PCD Lung DiseaseR01HL071798 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KNOWLES, MICHAEL R · 2004 to 2021
$7.2M
Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to PhenotypeR01HL117836 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI OSTROWSKI, LAWRENCE E · 2013 to 2023
$4.4M
NHLBI NIH HHS R01 HL071798NHLBI NIH HHS R01 HL117836NHLBI NIH HHS U54 HL096458NIDDK NIH HHS P30 DK065988
6 · The paper itself

Abstract

Cilia are essential to many diverse cellular processes. Although many major axonemal components have been identified and studied, how they interact to form a functional axoneme is not completely understood. To further our understanding of the protein composition of human airway cilia, we performed a semiquantitative analysis of ciliary axonemes using label-free LC/MS

Indexed as

AxonemeCiliaDyneinsGene Expression RegulationHumansProteinsProteomeProteomicsTubulinDyneinsProteinsProteomeTubulinairwayaxonemeciliadyneinmass spectrometryproteomicsradial spoketubulin

Identifiers

PMID28282151
PMCPMC5733142
OpenAlexW2594522669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.