Evidence map›Paper›PMID 28281573›Full record

ArticleScientific reports2017

Formulation for Oral Delivery of Lactoferrin Based on Bovine Serum Albumin and Tannic Acid Multilayer Microcapsules.

Ece Kilic, Marina V Novoselova, Su Hui Lim, Nikolay A Pyataev, Sergey I Pinyaev, Oleg A Kulikov, Olga A Sindeeva, Oksana A Mayorova, Regan Murney, Maria N Antipina and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review, role of lactoferrin in preventing preterm delivery.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023
    Review
  5. Article
  6. Article
  7. Review
  8. Potential of Lactoferrin in the Treatment of Lung Diseases.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Hard, Soft, and Hard-Pharmaceutics · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 4 countries.

Ece KilicInstitute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.
Marina V NovoselovaInstitute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.
Su Hui LimInstitute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.
Nikolay A PyataevNational Research Ogarev Mordovia State University, 68 Bolshevistskaya Str., Saransk, Republic of Mordovia, 430005, Russia.
Sergey I PinyaevNational Research Ogarev Mordovia State University, 68 Bolshevistskaya Str., Saransk, Republic of Mordovia, 430005, Russia.
Oleg A KulikovNational Research Ogarev Mordovia State University, 68 Bolshevistskaya Str., Saransk, Republic of Mordovia, 430005, Russia.
Olga A SindeevaN.G. Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov, 410012, Russia.
Oksana A MayorovaN.G. Chernyshevsky Saratov State University, 83 Astrakhanskaya Street, Saratov, 410012, Russia.
Regan MurneyAgResearch Limited, Ruakura Research Centre, Bisley Road, Private Bag 3123, Hamilton 3240, New Zealand.
Maria N AntipinaInstitute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.
Brendan HaighAgResearch Limited, Ruakura Research Centre, Bisley Road, Private Bag 3123, Hamilton 3240, New Zealand.
Gleb B SukhorukovSchool of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS, United Kingdom.
Maxim V KiryukhinInstitute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis, #08-03, 138634, Singapore.
National Research Mordovia State University · RUSaratov State University · RUAgResearch · NZInstitute of Materials Research and Engineering · SGAgency for Science, Technology and Research · SGNational University of Singapore · SGQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactoferrin (Lf) has considerable potential as a functional ingredient in food, cosmetic and pharmaceutical applications. However, the bioavailability of Lf is limited as it is susceptible to digestive enzymes in gastrointestinal tract. The shells comprising alternate layers of bovine serum albumin (BSA) and tannic acid (TA) were tested as Lf encapsulation system for oral administration. Lf absorption by freshly prepared porous 3 μm CaCO

Indexed as

LactoferrinSerum Albumin, BovineTanninsAdministration, OralAnimalsCapsulesCattleDrug Delivery SystemsFemaleMiceMice, Inbred BALB CCapsulesLactoferrinSerum Albumin, BovineTannins

Identifiers

PMID28281573
PMCPMC5344998
OpenAlexW2592487006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.