Evidence map›Paper›PMID 28281168›Full record

ReviewDigestive diseases and sciences2017

Epidemiology of Recurrent Acute and Chronic Pancreatitis: Similarities and Differences.

Jorge D Machicado, Dhiraj Yadav

2 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 83 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647097 narecruitingnot on this mapstarted 2022, after this paper: background citation

Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study

TypeinterventionalSponsorUniversity of PecsRan2022 to 2028Enrolled364ConditionsAcute Pancreatitis, Recurrent Acute PancreatitisArmsStandard intervention only, Standard intervention plus repeated intervention
NCT06364397 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Efficacy of ERCP in the Diagnosis and Treatment of Idiopathic Recurrent Acute Pancreatitis: a Randomized Controlled Trial

TypeinterventionalSponsorChanghai HospitalRan2024 to 2026Enrolled158ConditionsRecurrent Acute PancreatitisArmsERCP, Health education and conservative management of clinical routines
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Prophylactic abdominal drainage for pancreatic surgery.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Editorial: Dissecting the Natural History of Recurrent Pancreatitis.Alimentary pharmacology & therapeutics · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Development of a core outcome set for recurrent acute and chronic pancreatitis: Results of a Delphi poll.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2024
    Article
  19. Review
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jorge D MachicadoDivision of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, 200 Lothrop Street, M-2, C-Wing, Pittsburgh, PA, 15213, USA.
Dhiraj YadavDivision of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh Medical Center, 200 Lothrop Street, M-2, C-Wing, Pittsburgh, PA, 15213, USA. yadavd@upmc.edu.

Funding

UPMC Clinical Center for the Study of Chronic Pancreatitis and DiabetesU01DK108306 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Frederico G. S. Toledo, Dhiraj Yadav · 2015 to 2026
$6.4M
Digestive Diseases Training ProgramT32DK063922 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARTEEL, GAVIN E, YADAV, DHIRAJ · 2003 to 2022
$5.2M
NIDDK NIH HHS T32 DK063922NIDDK NIH HHS U01 DK108306
6 · The paper itself

Abstract

Emerging data in the past few years suggest that acute, recurrent acute (RAP), and chronic pancreatitis (CP) represent a disease continuum. This review discusses the similarities and differences in the epidemiology of RAP and CP. RAP is a high-risk group, comprised of individuals at varying risk of progression. The premise is that RAP is an intermediary stage in the pathogenesis of CP, and a subset of RAP patients during their natural course transition to CP. Although many clinical factors have been identified, accurately predicting the probability of disease course in individual patients remains difficult. Future studies should focus on providing more precise estimates of the risk of disease transition in a cohort of patients, quantification of clinical events during the natural course of disease, and discovery of biomarkers of the different stages of the disease continuum. Availability of clinically relevant endpoints and linked biomarkers will allow more accurate prediction of the natural course of disease over intermediate- or long-term-based characteristics of an individual patient. These endpoints will also provide objective measures for use in clinical trials of interventions that aim to alter the natural course of disease.

Indexed as

HumansIncidencePancreatitisPancreatitis, ChronicQuality of LifeRecurrenceSurvival AnalysisChronic pancreatitisEpidemiologyRecurrent acute pancreatitis

Identifiers

PMID28281168
PMCPMC5478431

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.