Evidence map›Paper›PMID 28281140›Full record

ArticleEnvironmental geochemistry and health2018

Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements.

Marina M S Cabral Pinto, A Paula Marinho-Reis, Agostinho Almeida, Carlos M Ordens, Maria M V G Silva, Sandra Freitas, Mário R Simões, Paula I Moreira, Pedro A Dinis, M Luísa Diniz and 2 more

Abstract read
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In one paragraph

Article in Environmental geochemistry and health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Cognitive reserve in ALS: the role of occupational skills and requirements.Amyotrophic lateral sclerosis & frontotemporal degeneration · 2024
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  11. Air pollution and multiple sclerosis: a comprehensive review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  12. Review
  13. Review
  14. Article
  15. Systematic Assessment of Health Risk from Metals in Surface Sediment of the Xiangjiang River, China.International journal of environmental research and public health · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Depressive Symptoms among Industrial Workers in Vietnam and Correlated Factors: A Multi-Site Survey.International journal of environmental research and public health · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marina M S Cabral PintoDepartment of Geosciences, Geobiotec Research Centre, University of Aveiro, 3810-193, Aveiro, Portugal. mcp@uc.pt.
A Paula Marinho-ReisDepartment of Geosciences, Geobiotec Research Centre, University of Aveiro, 3810-193, Aveiro, Portugal.
Agostinho AlmeidaLAQV/REQUIMTE, Department of Chemical Sciences, Laboratory of Applied Chemistry, Faculty of Pharmacy, Porto University, 4050-313, Porto, Portugal.
Carlos M OrdensUniversity College London Australia, Adelaide, South Australia, 5000, Australia.
Maria M V G SilvaDepartment of Earth Sciences, University of Coimbra, 3030-790, Coimbra, Portugal.
Sandra FreitasCNC-Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, 3030-548, Coimbra, Portugal.
Mário R SimõesCentro de Investigação do Núcleo de Estudos e Intervenção Cognitivo Comportamental (CINEICC), Universidade de Coimbra, Coimbra, Portugal.
Paula I MoreiraCNC-Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, 3030-548, Coimbra, Portugal.
Pedro A DinisDepartment of Earth Sciences, University of Coimbra, 3030-790, Coimbra, Portugal.
M Luísa DinizDepartment of Geosciences, Geobiotec Research Centre, University of Aveiro, 3810-193, Aveiro, Portugal.
Eduardo A Ferreira da SilvaDepartment of Geosciences, Geobiotec Research Centre, University of Aveiro, 3810-193, Aveiro, Portugal.
M Teresa Condesso de MeloCEris, DECivil, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.

Funding

Foundation for Science and the Technology SFRH/BPD/71030/2010
6 · The paper itself

Abstract

New lines of evidence suggest that less than 10% of neurodegenerative diseases have a strict genetic aetiology and other factors may be prevalent. Environmental exposures to potentially toxic elements appear to be a risk factor for Parkinson's, Alzheimer's and sclerosis diseases. This study proposes a multidisciplinary approach combining neurosciences, psychology and environmental sciences while integrating socio-economic, neuropsychological, environmental and health data. We present the preliminary results of a neuropsychological assessment carried out in elderly residents of the industrial city of Estarreja. A battery of cognitive tests and a personal questionnaire were administered to the participants. Multivariate analysis and multiple linear regression analysis were used to identify potential relationships between the cognitive status of the participants and environmental exposure to potentially toxic elements. The results suggest a relationship between urinary PTEs levels and the incidence of cognitive disorders. They also point towards water consumption habits and profession as relevant factors of exposure. Linear regression models show that aluminium (R

Indexed as

Environmental ExposureAgedCognitive DysfunctionEnvironmental PollutantsFemaleGroundwaterHumansIncidenceMaleMetals, HeavyNeuropsychological TestsPortugalRisk FactorsWater Pollutants, ChemicalEnvironmental PollutantsMetals, HeavyWater Pollutants, ChemicalEnvironmental exposureGroundwaterNeurodegenerative diseasesPotentially toxic elementsUrine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.