ArticleJournal of autism and developmental disorders2017
Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series.
Article in Journal of autism and developmental disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- [Towards an early differential diagnosis in autism spectrum disorders and fragile X syndrome. A systematic review].Revista de neurologia · 2022Pooled it
- Novel CTNNB1 Gene Variants in Spanish CTNNB1 Syndrome Patients: Clinical and Psychological Manifestations.Journal of autism and developmental disorders · 2026Article
- Assessing Autism Co-Occurrence in Fragile X Syndrome: Proposing a Preliminary CARS-2 Cut-Off Score.Journal of autism and developmental disorders · 2025Article
- Hippocampal Upregulation of Complement Component C3 in Response to Lipopolysaccharide Stimuli in a Model of Fragile-X Syndrome.Current issues in molecular biology · 2023Article
- Hyperacusis in the AdultInternational journal of molecular sciences · 2023Article
- Neurodevelopmental dimensional assessment of young children at high genomic risk of neuropsychiatric conditions.JCPP advances · 2023Article
- Distinct social attention profiles in preschoolers with autism contrasted to fragile X syndrome.Autism research : official journal of the International Society for Autism Research · 2023Article
- Pragmatic Profiles of Adults with Fragile X Syndrome and Williams Syndrome.Brain sciences · 2022Article
- Retinoic Acid Supplementation Rescues the Social Deficits inFrontiers in genetics · 2022Article
- Concurrent Associations between Expressive Language Ability and Independence in Adolescents and Adults with Fragile X Syndrome.Brain sciences · 2021Article
- Early behavioral and physiological markers of social anxiety in infants with fragile X syndrome.Journal of neurodevelopmental disorders · 2021Article
- Attention Bias and Prodromal Anxiety Symptoms in Toddlers With Fragile X Syndrome and Down Syndrome.American journal on intellectual and developmental disabilities · 2021Article
- Trajectories of Heart Activity Across Infancy to Early Childhood Differentially Predict Autism and Anxiety Symptoms in Fragile X Syndrome.Frontiers in psychiatry · 2021Article
- Cardiac Startle Response and Clinical Outcomes in Preschool Children With Fragile X Syndrome and Autism Spectrum Disorder.Frontiers in psychiatry · 2021Article
- Neural Correlates of Infant Face Processing and Later Emerging Autism Symptoms in Fragile X Syndrome.Frontiers in psychiatry · 2021Article
- An Observational Study of Social Interaction Skills and Behaviors in Cornelia de Lange, Fragile X and Rubinstein-Taybi Syndromes.Journal of autism and developmental disorders · 2020Observational
- Emergence and rate of autism in fragile X syndrome across the first years of life.Development and psychopathology · 2020Article
- Evaluating Social Interactions Using the Autism Screening Instrument for Education Planning-3rd Edition (ASIEP-3): Interaction Assessment in Children and Adults with Fragile X Syndrome.Brain sciences · 2020Article
- Gesture Frequency and Function in Infants With Fragile X Syndrome and Infant Siblings of Children With Autism Spectrum Disorder.Journal of speech, language, and hearing research : JSLHR · 2019Article
- ASD Comorbidity in Fragile X Syndrome: Symptom Profile and Predictors of Symptom Severity in Adolescent and Young Adult Males.Journal of autism and developmental disorders · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
No studies to date have prospectively examined early autism spectrum disorder (ASD) markers in infants with fragile X syndrome (FXS), who are at elevated risk for ASD. This paper describes the developmental profiles of eight infants with FXS from 9 to 24 months of age. Four meet diagnostic criteria for ASD at 24 months of age, and four do not. Trends in these case studies suggest that early social-communicative deficits differentiate infants with and without later ASD diagnoses in ways that are similar to later-born siblings of children with ASD. Repetitive behaviors and cognitive and adaptive impairments are present in all FXS infants throughout development, suggesting that these deficits reflect the general FXS phenotype and not ASD in FXS specifically.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.