ArticleSurgical endoscopy2017
Short-term outcomes of laparoscopic vs. open liver resection for hepatocellular adenoma: a multicenter propensity score adjustment analysis by the AFC-HCA-2013 study group.
Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Open versus laparoscopic hepatic resection for hepatocellular carcinoma: a systematic review and meta-analysis.Surgical endoscopy · 2019Pooled it
- Minimally invasive versus open liver resection for benign disease: analysis of textbook outcomes according to difficulty of resections and role of the robotic approach.Surgical endoscopy · 2026Article
- A Comparative Study of Laparoscopic and Open Approaches for Right Hemihepatectomy in Hepatocellular Carcinoma Patients: Safety and Short-Term Outcomes.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Anatomic Laparoscopic Partial Hepatectomy of a Segment 4a B-Catenin Mutated Adenoma.Annals of surgical oncology · 2023Article
- A Scoping Review of the Classification, Diagnosis, and Management of Hepatic Adenomas.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Augmented reality in laparoscopic liver resection evaluated on an ex-vivo animal model with pseudo-tumours.Surgical endoscopy · 2022Article
- Laparoscopic versus open right posterior sectionectomy: an international, multicenter, propensity score-matched evaluation.Surgical endoscopy · 2021Article
- Hepatocellular Carcinoma Arising from Hepatocellular Adenoma in an Elderly Male Patient.Journal of liver cancer · 2021Article
- A Shifting Paradigm in Diagnosis and Management of Hepatic Adenoma.Annals of surgical oncology · 2020Article
- New insights in the management of Hepatocellular Adenoma.Liver international : official journal of the International Association for the Study of the Liver · 2020Review
- Case of resected multiple hepatocellular adenomas in a young man with severe obesity.Surgical case reports · 2019Article
- Laparoscopic combined resection of liver metastases and colorectal cancer: a multicenter, case-matched study using propensity scores.Surgical endoscopy · 2019Article
- Current Approaches in the Management of Hepatic Adenomas.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Review
- Current topics in the surgical treatments for hepatocellular carcinoma.Annals of gastroenterological surgery · 2018Review
Corrections and comments
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Authors and funding
13 authors at 11 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with hepatocellular adenomas are, in selected cases, candidates for liver resection, which can be approached via laparoscopy or laparotomy. The present study aimed to investigate the effects of the surgical approach on the postoperative morbidities of both minor and major liver resections.
methodsIn this multi-institutional study, all patients who underwent open or laparoscopic hepatectomies for hepatocellular adenomas between 1989 and 2013 in 27 European centers were retrospectively reviewed. A multiple imputation model was constructed to manage missing variables. Comparisons of both the overall rate and the types of complications between open and laparoscopic hepatectomy were performed after propensity score adjustment (via the standardized mortality ratio weighting method) on the factors that influenced the choice of the surgical approach.
resultsThe laparoscopic approach was selected in 208 (38%) of the 533 included patients. There were 194 (93%) women. The median age was 38.9 years. After the application of multiple imputation, 208 patients who underwent laparoscopic operations were compared with 216 patients who underwent laparotomic operations. After adjustment, there were 20 (9.6%) major liver resections in the laparoscopy group and 17 (7.9%) in the open group. The conversion rate was 6.3%. The two surgical approaches exhibited similar postoperative morbidity rates and severities. Laparoscopic resection was associated with significantly less blood loss (93 vs. 196 ml, p < 0.001), a less frequent need for pedicle clamping (21 vs. 40%, p = 0.002), a reduced need for transfusion (8 vs. 24 red blood cells units, p < 0.001), and a shorter hospital stay (5 vs. 7 days, p < 0.001). The mortality was nil.
conclusionsLaparoscopy can achieve short-term outcomes similar to those of open surgery for hepatocellular adenomas and has the additional benefits of a reduced blood loss, need for transfusion, and a shorter hospital stay.
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