ReviewFrontiers in pediatrics2017
Cerebral Tissue Oxygenation during Immediate Neonatal Transition and Resuscitation.
Review in Frontiers in pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07477093 (Evaluation of the Effects of Spinal and General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of the Effects of Spinal and General Anesthesia on Neonatal Cerebral Oxygenation During Cesarean Section
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Brain oxygenation monitoring during neonatal stabilization and resuscitation and its potential for improving preterm infant outcomes: a systematic review and meta-analysis with Bayesian analysis.European journal of pediatrics · 2025Pooled it
- Cerebral regional tissue Oxygen Saturation to Guide Oxygen Delivery in preterm neonates during immediate transition after birth (COSGOD III): multicentre randomised phase 3 clinical trial.BMJ (Clinical research ed.) · 2023Trial
- Cerebral Oxygenation during the First 15 Minutes after Birth and Short-Term Outcome Measured by the Motor Optimality Score-Revised in Preterm Infants.Neonatology · 2026Article
- Impact of cerebral oxygenation-guided resuscitation during immediate postnatal transition on brain injury and brain growth detected by MRI in very preterm neonates: a secondary outcome analysis of the multicenter randomized phase 3 clinical COSGOD III trial.Italian journal of pediatrics · 2026Article
- Review
- Hemodynamic Changes in the Transition Period in the Preterm and Term Infant: Basic Concepts.Turkish archives of pediatrics · 2025Article
- Acid base and metabolic parameters of the umbilical cord blood and cerebral oxygenation immediately after birth.Frontiers in pediatrics · 2024Article
- A survey on management practices of hypotension in preterm neonates: an Indian perspective.Frontiers in pediatrics · 2024Article
- Insights into Neonatal Cerebral Autoregulation by Blood Pressure Monitoring and Cerebral Tissue Oxygenation: A Qualitative Systematic Review.Children (Basel, Switzerland) · 2023Review
- Examining time-frequency mechanisms of full-fledged deep sleep development in newborns of different gestational age in the first days of their postnatal development.Scientific reports · 2022Article
- Correlation between arterial blood pressures and regional cerebral oxygen saturation in preterm neonates during postnatal transition-an observational study.Frontiers in pediatrics · 2022Article
- A Single-Center Observational Clinical Study on Factors Associated with Regional Cerebral Oxygen Saturation in Full-Term Newborn Infants During Birth Transition.Medical science monitor : international medical journal of experimental and clinical research · 2021Observational
- [Near-infrared spectroscopy : Technique, development, current use and perspectives].Der Anaesthesist · 2021Review
- The hidden consequence of intraventricular hemorrhage: persistent cerebral desaturation after IVH in preterm infants.Pediatric research · 2021Article
- Excess cerebral oxygen delivery follows return of spontaneous circulation in near-term asphyxiated lambs.Scientific reports · 2020Article
- Optimizing oxygen therapy for preterm infants at birth: Are we there yet?Seminars in fetal & neonatal medicine · 2020Review
- Heart Rate Assessment during Neonatal Resuscitation.Healthcare (Basel, Switzerland) · 2020Review
- Cerebral Oxygen Changes in Neonates During Immediate Transition After Birth and Early Life: An Observational Study.Drug design, development and therapy · 2020Observational
- Article
- Temporal evolution of quantitative EEG within 3 days of birth in early preterm infants.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article provides a review of cerebral tissue oxygenation during immediate transition after birth in human neonates. Recommended routine monitoring, especially if resuscitation is needed, during this period includes arterial oxygen saturation and heart rate measured by pulse oximetry and electrocardiogram. However, there is increasing interest to monitor in addition with near-infrared spectroscopy (NIRS) the oxygenation of the brain. There is a different pattern of increase between cerebral tissue oxygenation and arterial oxygen saturation during the immediate transition, with cerebral tissue oxygenation reaching a plateau faster than arterial oxygen saturation. Differences can be explained, since cerebral tissue oxygenation is not only affected by arterial oxygen saturation but also by cerebral blood flow, hemoglobin content, and cerebral oxygen consumption. Normal values have already been established for different devices, gestational ages, and modes of delivery in neonates without any medical support. Cerebral hypoxia during immediate transition might cause brain damage. In preterm neonates with cerebral hemorrhage evolving in the first week after birth, the cerebral tissue oxygenation is already lower in the first minutes after birth compared to preterm neonates without cerebral hemorrhage. Using cerebral NIRS in combination with intervention guidelines has been shown to reduce the burden of cerebral hypoxia in preterm neonates. Cerebral tissue oxygenation during immediate transition seems to have an impact on outcome, whereby NIRS monitoring is feasible and has the advantage of continuous, non-invasive recording. The impact of NIRS monitoring and interventions on short- and long-term outcomes still need to be evaluated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.