Evidence map›Paper›PMID 28280451›Full record

ArticleMacromolecular materials and engineering2016

Effects of Terminal Sterilization on PEG-Based Bioresorbable Polymers Used in Biomedical Applications.

Divya Bhatnagar, Koustubh Dube, Vinod B Damodaran, Ganesan Subramanian, Kenneth Aston, Frederick Halperin, Meiyu Mao, Kurt Pricer, N Sanjeeva Murthy, Joachim Kohn

Open access · greenAbstract read
In one paragraph

Article in Macromolecular materials and engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
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  10. Frontiers in microbiology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Divya BhatnagarNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Koustubh DubeNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Vinod B DamodaranNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Ganesan SubramanianNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Kenneth AstonJohnson & Johnson Sterility Assurance, 930, US 202, Raritan, NJ 08669, USA.
Frederick HalperinJohnson & Johnson Sterility Assurance, 930, US 202, Raritan, NJ 08669, USA.
Meiyu MaoJohnson & Johnson Sterility Assurance, 930, US 202, Raritan, NJ 08669, USA.
Kurt PricerJohnson & Johnson Sterility Assurance, 930, US 202, Raritan, NJ 08669, USA.
N Sanjeeva MurthyNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Joachim KohnNJ Centre for Biomaterials, Rutgers-The State University of New Jersey, 145 Bevier Road, Piscataway, NJ 08854, USA.
Rutgers, The State University of New Jersey · USJohnson & Johnson (United States) · US

Funding

RESBIO - the Technology Resource for Polymeric BiomaterialsP41EB001046 · NIBIB · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI KOHN, JOACHIM B. · 2003 to 2017
$17.0M
An engineered graft to encourage preferential motor reinnervation following peripR01NS078385 · NINDS · RUTGERS, THE STATE UNIV OF N.J. · PI KOHN, JOACHIM B., SCHACHNER, MELITTA · 2012 to 2016
$2.9M
NIBIB NIH HHS P41 EB001046NINDS NIH HHS R01 NS078385
6 · The paper itself

Abstract

The effects of ethylene oxide (EO), vaporized hydrogen peroxide (VHP), gamma (γ) radiation, and electron-beam (E-beam) on the physiochemical and morphological properties of medical device polymers are investigated. Polymers with ether, carbonate, carboxylic acid, amide and ester functionalities are selected from a family of poly(ethylene glycol) (PEG) containing tyrosine-derived polycarbonates (TyrPCs) to include slow, medium, fast, and ultrafast degrading polymers. Poly(lactic acid) (PLA) is used for comparison. Molecular weight (

Indexed as

biodegradablebiomaterialspoly(ethylene glycol)sterilizationstructure–property relations

Identifiers

PMID28280451
PMCPMC5340269
OpenAlexW2466084804

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.