ArticleInternational journal of obesity (2005)2017
Obesity/overweight reduces the risk of active tuberculosis: a nationwide population-based cohort study in Taiwan.
Article in International journal of obesity (2005), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Diabetes as a risk factor for tuberculosis disease.The Cochrane database of systematic reviews · 2024Pooled it
- Undernutrition as a risk factor for tuberculosis disease.The Cochrane database of systematic reviews · 2024Pooled it
- Protective efficacy of 6-week regimen for latent tuberculosis infection treatment in rural China: 5-year follow-up of a randomised controlled trial.The European respiratory journal · 2022Trial
- Prevalence and determinants of metabolic abnormalities among adult tuberculosis patients at Gondar Town, Northwest Ethiopia: an institution-based comparative cross-sectional study.BMC infectious diseases · 2026Article
- Association of overweight with treatment outcomes in pulmonary tuberculosis.BMC infectious diseases · 2025Article
- Alcohol Consumption of Male Tuberculosis Index Cases and Tuberculosis Transmission Among Social Contacts in Puducherry, India: A Cross-Sectional Analytical Study.Tropical medicine and infectious disease · 2025Article
- Tuberculosis treatment failure: what are the risk factors? A comprehensive literature review.Multidisciplinary respiratory medicine · 2025Article
- Prevalence and risk factors of high blood pressure among persons assessed for TB at three health facilities in Lusaka, Zambia.Frontiers in tuberculosis · 2025Article
- Macrophages, Metabolism, Mitochondria, Circadian Rhythmicity and the Pathogen: The Multidimensional Nature of Tuberculosis.Results and problems in cell differentiation · 2024Review
- Ambient PMEnvironmental health and preventive medicine · 2023Article
- Mouse Models forPathogens (Basel, Switzerland) · 2022Review
- Association of underweight status with the risk of tuberculosis: a nationwide population-based cohort study.Scientific reports · 2022Article
- Dose-response relationship between body mass index and tuberculosis in China: a population-based cohort study.BMJ open · 2022Article
- Association between body mass index and newly diagnosed drug-resistant pulmonary tuberculosis in Shandong, China from 2004 to 2019.BMC pulmonary medicine · 2021Article
- Changes in Nutritional Status in Pulmonary Tuberculosis: Longitudinal Changes in BMI According to Acid-Fast Bacilli Smear Positivity.Journal of clinical medicine · 2020Article
- Patterns of Antiretroviral Therapy Use and Immunologic Profiles at Enrollment in the REPRIEVE Trial.The Journal of infectious diseases · 2020 · on this mapArticle
- Article
- Host Transcriptomics as a Tool to Identify Diagnostic and Mechanistic Immune Signatures of Tuberculosis.Frontiers in immunology · 2019Review
- A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity.BMC systems biology · 2018Article
- Relative risk of all-cause mortality in patients with nontuberculous mycobacterial lung disease in a US managed care population.Respiratory medicine · 2018Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObesity affects immune function by increasing the number of T helper lymphocytes, which may reduce the risk of tuberculosis (TB) infection. However, the effect of obesity on TB development has not been extensively studied. This nationwide population-based cohort study investigated the effect of obesity on TB development in Taiwanese adults.
methodsWe included 46 028 adult participants (age ⩾18 years) from three rounds (2001, 2005 and 2009) of the Taiwan National Health Interview Survey. Obesity and overweight were defined as a body mass index (BMI) ⩾27 and 24-26.9 (kg/m
resultsIn total, 241 new cases of active TB occurred during the study period. Obesity (adjusted odds ratio [AOR], 0.43; 95% confident interval [CI], 0.28-0.67) and overweight (AOR, 0.67; 95% CI, 0.49-0.91) were associated with lower risk of incident TB, after adjusting for demographic characteristics and comorbidities. There was a linear dose-response relation of BMI with active TB incidence (AOR per unit change in BMI, 0.92; 95% CI, 0.88-0.95; P <0.001).
conclusionObesity and overweight are associated with lower risk of active TB. Future studies should investigate the underlying mechanisms and clinical and epidemiological consequences of these findings.
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