Evidence map›Paper›PMID 28280245›Full record

ArticleThe Journal of biological chemistry2017

Variable region in streptococcal M-proteins provides stable binding with host fibrinogen for plasminogen-mediated bacterial invasion.

Kristofor Glinton, Julia Beck, Zhong Liang, Cunjia Qiu, Shaun W Lee, Victoria A Ploplis, Francis J Castellino

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. A Putative Interaction between the Transmembrane Domains ofThe journal of physical chemistry. B · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kristofor GlintonFrom the W.M. Keck Center for Transgene Research and.
Julia BeckFrom the W.M. Keck Center for Transgene Research and.
Zhong LiangFrom the W.M. Keck Center for Transgene Research and.
Cunjia QiuFrom the W.M. Keck Center for Transgene Research and.
Shaun W LeeFrom the W.M. Keck Center for Transgene Research and.
Victoria A PloplisFrom the W.M. Keck Center for Transgene Research and.
Francis J CastellinoFrom the W.M. Keck Center for Transgene Research and fcastell@nd.edu.
University of Notre Dame · US

Funding

STRUCTURE-FUNCTION STUDIES ON PLASMINOGEN AND PLASMINR01HL013423 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J, LEE, SHAUN · 1985 to 2021
$7.9M
STRUCTURE/FUNCTION STUDIES ON PLASMINOGEN AND PLASMINR37HL013423 · NHLBI · UNIVERSITY OF NOTRE DAME · PI CASTELLINO, FRANCIS J · 1990 to 1999
–
NHLBI NIH HHS R01 HL013423NHLBI NIH HHS R37 HL013423
6 · The paper itself

Abstract

Dimeric M-proteins (M-Prt) in group A

Indexed as

Host-Pathogen InteractionsAnimalsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsCell WallDrosophilaEscherichia coliFibrinogenFibrinolysisHumansPhylogenyPlasminogenProtein BindingProtein DomainsRecombinant ProteinsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsFibrinogenPlasminogenRecombinant Proteinsstreptococcal M proteinbacterial pathogenesisbiophysicscell surface proteinfibrinogenfibrinolysisM-protein

Identifiers

PMID28280245
PMCPMC5399124
OpenAlexW2591899840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.