Evidence map›Paper›PMID 28280113›Full record

ArticleJournal of lipid research2017

An HPLC-CAD/fluorescence lipidomics platform using fluorescent fatty acids as metabolic tracers.

Vanessa H Quinlivan, Meredith H Wilson, Josef Ruzicka, Steven A Farber

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. PeakClimber: A software tool for the accurate quantification of complex HPLC chromatograms.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Zebrafish ApoB-Containing Lipoprotein Metabolism: A Closer Look.Arteriosclerosis, thrombosis, and vascular biology · 2024
    Review
  8. Article
  9. From worms to humans: Understanding intestinal lipid metabolism via model organisms.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2023
    Review
  10. Zebra-Sphinx: Modeling Sphingolipidoses in Zebrafish.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
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  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Vanessa H QuinlivanDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD 21218.
Meredith H WilsonDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD 21218.
Josef RuzickaThermo Fisher Scientific, Somerset, NJ 08873.
Steven A FarberDepartment of Embryology, Carnegie Institution for Science, Baltimore, MD 21218; farber@ciwemb.edu.
Department of Embryology · USCarnegie Institution for Science · USThermo Fisher Scientific (United States) · US

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
Systematic Vertebrate Functional GenomicsR01GM063904 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI EKKER, STEPHEN CARL · 2001 to 2025
$10.7M
Identifying genes required for digestive physiology and lipid metabolismR01DK093399 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI STEVEN A FARBER, John F Rawls · 2013 to 2026
$7.6M
Cellular and Molecular BiologyT32GM141804 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI John Kim · 2021 to 2026
$5.1M
Mechanisms of cytoplasmic lipid droplet regulation in the intestineF32DK109592 · NIDDK · CARNEGIE INSTITUTION OF WASHINGTON, D.C. · PI WILSON, MEREDITH H · 2016 to 2018
$173k
In vivo imaging to evaluate the effect of PUFAs on alcoholic fatty liver diseaseF31AA023142 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI QUINLIVAN-REPASI, VANESSA HELEN · 2014 to 2016
$129k
NIAAA NIH HHS F31 AA023142NIDDK NIH HHS F32 DK109592NIDDK NIH HHS R01 DK093399NIGMS NIH HHS R01 GM063904NIGMS NIH HHS T32 GM007231NIGMS NIH HHS T32 GM141804
6 · The paper itself

Abstract

Fluorescent lipids are important tools for live imaging in cell culture and animal models, yet their metabolism has not been well-characterized. Here we describe a novel combined HPLC and LC-MS/MS method developed to characterize both total lipid profiles and the products of fluorescently labeled lipids. Using this approach, we found that lipids labeled with the fluorescent tags, 4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-

Indexed as

AerosolsAnimalsBiological TransportBoron CompoundsCholesterol, DietaryChromatography, High Pressure LiquidEnterocytesEsterificationFatty AcidsFluorescent DyesLarvaMetabolomicsSpectrometry, FluorescenceZebrafish4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneAerosolsBoron CompoundsCholesterol, DietaryFatty AcidsFluorescent DyesBODIPYcharged aerosol detectioncholesterol/metabolismdiet and dietary lipidsfatty acid/metabolismhigh-performance liquid chromatographyisotopic tracerslipids/chemistrymass spectrometryzebrafish

Identifiers

PMID28280113
PMCPMC5408600
OpenAlexW2592680546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.