Evidence map›Paper›PMID 28280106›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2017

Dynamics of middle cerebral artery blood flow velocity during moderate-intensity exercise.

Sandra A Billinger, Jesse C Craig, Sarah J Kwapiszeski, Jason-Flor V Sisante, Eric D Vidoni, Rebecca Maletsky, David C Poole

Registry-linked trialAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05131217 (Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults), which is not on this map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05131217 nacompletednot on this mapstarted 2022, after this paper: background citation

Effects of Acute Exercise Intensity on Cerebral Blood Flow and Cognitive Function in Older Adults

TypeinterventionalSponsorUniversity of VirginiaRan2022 to 2023Enrolled13ConditionsAging WellArmsAcute bout of Continuous Moderate Intensity Exercise, Acute bout of High Intensity Interval Training, Control
3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
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  5. Sleep Alters the Velocity of Physiological Brain Pulsations in Humans.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  11. APOE4 carriers display loss of anticipatory cerebrovascular regulation across the Alzheimer's disease continuum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  12. Article
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  18. Lower middle cerebral artery blood velocity during low-volume high-intensity interval exercise in chronic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sandra A BillingerDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas; sbillinger@kumc.edu.
Jesse C CraigDepartment of Kinesiology, Kansas State University, Manhattan, Kansas.
Sarah J KwapiszeskiDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas.
Jason-Flor V SisanteDepartment of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, Kansas.
Eric D VidoniUniversity of Kansas Alzheimer's Disease Center, Fairway, Kansas.
Rebecca Maletsky
David C PooleDepartment of Kinesiology, Kansas State University, Manhattan, Kansas.

Funding

University of Kansas Alzheimer's Disease Core CentersP30AG035982 · NIA · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SWERDLOW, RUSSELL H. · 2011 to 2020
$16.6M
NIA NIH HHS P30 AG035982
6 · The paper itself

Abstract

The dynamic response to a stimulus such as exercise can reveal valuable insights into systems control in health and disease that are not evident from the steady-state perturbation. However, the dynamic response profile and kinetics of cerebrovascular function have not been determined to date. We tested the hypotheses that bilateral middle cerebral artery blood flow mean velocity (MCA

Indexed as

AdultAgedBlood Flow VelocityBrainCerebrovascular CirculationExerciseFemaleHumansKineticsMaleMiddle Cerebral ArteryReproducibility of ResultsRestStrokeYoung Adultagingblood flow velocitybrain blood flowmiddle cerebral arterystroke

Identifiers

PMID28280106
PMCPMC5451537

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.