Evidence map›Paper›PMID 28280090›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Pooled Clustering of High-Grade Serous Ovarian Cancer Gene Expression Leads to Novel Consensus Subtypes Associated with Survival and Surgical Outcomes.

Chen Wang, Sebastian M Armasu, Kimberly R Kalli, Matthew J Maurer, Ethan P Heinzen, Gary L Keeney, William A Cliby, Ann L Oberg, Scott H Kaufmann, Ellen L Goode

Open access · greenAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. The KPROCS Study: A Real-World and Research Resource to Investigate Multilevel Determinants of Ovarian Cancer Treatment and Survival.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. BeyondmedRxiv : the preprint server for health sciences · 2025
    Article
  8. Patterns of Associations with Epidemiologic Factors by High-Grade Serous Ovarian Cancer Gene Expression Subtypes.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  9. Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  10. Molecular Subtypes of High-Grade Serous Ovarian Cancer across Racial Groups and Gene Expression Platforms.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  11. Article
  12. Adipocyte Microenvironment in Ovarian Cancer: A Critical Contributor?International journal of molecular sciences · 2023
    Review
  13. Concurrent RB1 loss andmedRxiv : the preprint server for health sciences · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Methylation Signature Implicated in Immuno-Suppressive Activities in Tubo-Ovarian High-Grade Serous Carcinoma.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
  18. Review
  19. Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chen WangDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Sebastian M ArmasuDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Kimberly R KalliDepartment of Oncology, Mayo Clinic, Rochester, Minnesota.
Matthew J MaurerDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Ethan P HeinzenDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Gary L KeeneyDepartment of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota.
William A ClibyDepartment of Gynecologic Surgery, Mayo Clinic, Rochester, Minnesota.
Ann L ObergDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Scott H KaufmannDepartment of Oncology, Mayo Clinic, Rochester, Minnesota.
Ellen L GoodeDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota. egoode@mayo.edu.
Mayo Clinic in Florida · USMayo Clinic · US

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI Felicity Enders · 1985 to 2026
$151.3M
Use of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancerP50CA136393 · NCI · MAYO CLINIC ROCHESTER · PI Zhenkun Lou · 2009 to 2026
$37.0M
Genetic Variation in the NF-kappaB Pathway and Ovarian Cancer EtiologyR01CA122443 · NCI · MAYO CLINIC ROCHESTER · PI GOODE, ELLEN L. · 2007 to 2012
$2.7M
NCI NIH HHS P30 CA015083NCI NIH HHS P50 CA136393NCI NIH HHS R01 CA122443
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overCystadenocarcinoma, SerousDisease-Free SurvivalFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedNeoadjuvant TherapyNeoplasm GradingNeoplasm ProteinsNeoplasm, ResidualOvarian NeoplasmsPrognosisTreatment OutcomeNeoplasm Proteins

Identifiers

PMID28280090
PMCPMC5567822
OpenAlexW2591636916

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.