Evidence map›Paper›PMID 28280056›Full record

ArticleGenetics2017

Comparative Analyses of Selection Operating on Nontranslated Intergenic Regions of Diverse Bacterial Species.

Harry A Thorpe, Sion C Bayliss, Laurence D Hurst, Edward J Feil

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 85 citations in OpenAlex.

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  13. StORF-Reporter: finding genes between genes.Nucleic acids research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Harry A ThorpeDepartment of Biology and Biochemistry, The Milner Centre for Evolution, University of Bath, BA2 7AY, United Kingdom.ORCID 0000-0001-5895-3232
Sion C BaylissDepartment of Biology and Biochemistry, The Milner Centre for Evolution, University of Bath, BA2 7AY, United Kingdom.ORCID 0000-0002-5997-2002
Laurence D HurstDepartment of Biology and Biochemistry, The Milner Centre for Evolution, University of Bath, BA2 7AY, United Kingdom.ORCID 0000-0001-6952-6797
Edward J FeilDepartment of Biology and Biochemistry, The Milner Centre for Evolution, University of Bath, BA2 7AY, United Kingdom e.feil@bath.ac.uk.ORCID 0000-0003-1446-6744
University of Bath · GB

Funding

Medical Research Council G1000803Medical Research Council MR/L015080/1
6 · The paper itself

Abstract

Nontranslated intergenic regions (IGRs) compose 10-15% of bacterial genomes, and contain many regulatory elements with key functions. Despite this, there are few systematic studies on the strength and direction of selection operating on IGRs in bacteria using whole-genome sequence data sets. Here we exploit representative whole-genome data sets from six diverse bacterial species:

Indexed as

Genome, BacterialRegulatory Sequences, Nucleic AcidConserved SequenceDNA, IntergenicEscherichia coliEvolution, MolecularKlebsiella pneumoniaeMycobacterium tuberculosisRibosomesRNA, UntranslatedSalmonella entericaStaphylococcus aureusStreptococcus pneumoniaeDNA, IntergenicRNA, Untranslatedbacterial genomicsintergenic regions (IGRs)purifying selectionwhole-genome sequencing

Identifiers

PMID28280056
PMCPMC5419481
OpenAlexW2592012729

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.