Evidence map›Paper›PMID 28279983›Full record

ArticleGenes & development2017

A microRNA family exerts maternal control on sex determination in

Katherine McJunkin, Victor Ambros

Abstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Widespread destabilization ofRNA (New York, N.Y.) · 2024
    Article
  8. Review
  9. A Compilation of the Diverse miRNA Functions inInternational journal of molecular sciences · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Sex Determination in Nematode Germ Cells.Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation · 2022
    Review
  15. The role of RNA-binding proteins in orchestrating germline development inFrontiers in cell and developmental biology · 2022
    Review
  16. Disrupting interaction between miR-132 andFrontiers in molecular neuroscience · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. The multifaceted roles of microRNAs in differentiation.Current opinion in cell biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katherine McJunkinProgram in Molecular Medicine, RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Victor AmbrosProgram in Molecular Medicine, RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
GENETIC CONTROL OF NEMATODE DEVELOPMENTR01GM034028 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI AMBROS, VICTOR · 1985 to 2018
$7.0M
Molecular Mechanisms of microRNA and miRISC turnoverK99GM113063 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCJUNKIN, KATHERINE · 2015 to 2016
$162k
Genetic analysis of post-transcriptional modulators of microRNAs in C. elegansF32GM097895 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MCJUNKIN, KATHERINE · 2011 to 2013
$155k
NIGMS NIH HHS F32 GM097895NIGMS NIH HHS K99 GM113063NIGMS NIH HHS R01 GM034028NIH HHS P40 OD010440
6 · The paper itself

Abstract

Gene expression in early animal embryogenesis is in large part controlled post-transcriptionally. Maternally contributed microRNAs may therefore play important roles in early development. We elucidated a major biological role of the nematode

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsEmbryonic DevelopmentFemaleGene Expression Regulation, DevelopmentalMaleMicroRNAsMutationRNA-Binding ProteinsSex Determination ProcessesCaenorhabditis elegans ProteinsMicroRNAsMIRN35 microRNA, C elegansRNA-Binding Proteinsembryonic developmentmaternal controlmicroRNAsmir-35–41mir-35–42sex determination

Identifiers

PMID28279983
PMCPMC5358761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.