Evidence map›Paper›PMID 28279675›Full record

ArticleBiochimica et biophysica acta. Bioenergetics2017

Synchronism in mitochondrial ROS flashes, membrane depolarization and calcium sparks in human carcinoma cells.

Andrey V Kuznetsov, Sabzali Javadov, Valdur Saks, Raimund Margreiter, Michael Grimm

Abstract read
In one paragraph

Article in Biochimica et biophysica acta. Bioenergetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  6. Review
  7. Bioelectricity in dental medicine: a narrative review.Biomedical engineering online · 2024
    Review
  8. Review
  9. ROS are evolutionary conserved cell-to-cell stress signals.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  10. Article
  11. The mitochondrial CaScientific reports · 2022
    Article
  12. Review
  13. Reactive oxygen species signalling in plant stress responses.Nature reviews. Molecular cell biology · 2022
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Andrey V KuznetsovCardiac Surgery Laboratory, Department of Heart Surgery, Medical University of Innsbruck, Innsbruck A-6020, Austria. Electronic address: andrey.kuznetsov@tirol-kliniken.at.
Sabzali JavadovDepartment of Physiology, School of Medicine, University of Puerto Rico, San Juan, PR 00936-5067, USA.
Valdur SaksLaboratory of Fundamental and Applied Bioenergetics, INSERM U884, University Joseph Fourier, Grenoble, France.
Raimund MargreiterDepartment of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Michael GrimmCardiac Surgery Laboratory, Department of Heart Surgery, Medical University of Innsbruck, Innsbruck A-6020, Austria.
Innsbruck Medical University · ATInserm · FRUniversity of Puerto Rico System · PR

Funding

Mitochondrial Permeability Transition as a Target for Cardioprotection in Heart FSC1HL118669 · NHLBI · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI JAVADOV, SABZALI · 2012 to 2016
$1.3M
NHLBI NIH HHS SC1 HL118669
6 · The paper itself

Abstract

Mitochondria are major producers of reactive oxygen species (ROS) in many cells including cancer cells. However, complex interrelationships between mitochondrial ROS (mitoROS), mitochondrial membrane potential (ΔΨm) and Ca

Indexed as

Calcium SignalingMembrane Potential, MitochondrialAdenocarcinomaAntioxidantsBreast NeoplasmsCell Line, TumorColonic NeoplasmsCyclosporineFluoresceinsHumansMicroscopy, ConfocalMicroscopy, FluorescenceMitochondriaMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreOxidative StressAntioxidantsCyclosporinediacetyldichlorofluoresceinFluoresceinsMitochondrial Membrane Transport ProteinsMitochondrial Permeability Transition PoreReactive Oxygen SpeciesRecombinant ProteinsRhodaminesSuperoxide Dismutasetetramethylrhodamine methyl esterCa(2+) sparksCarcinoma cellsMembrane potentialMitochondriaROS flashes

Identifiers

PMID28279675
PMCPMC5972832
OpenAlexW2593744497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.