ReviewSchizophrenia research2017
Sex-dependent mental illnesses and mitochondria.
Review in Schizophrenia research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Global burden of mental disorders among women of child-bearing age, 1990-2021, with projections to 2050.European archives of psychiatry and clinical neuroscience · 2026Article
- The Dopaminergic Energy Crisis of Adolescent Depression: Mitochondrial Bioenergetics Control of Nucleus Accumbens Signaling.Neuroscience bulletin · 2026Article
- Mitochondrial dysfunction in PTSD: A mechanism to understand trauma susceptibility?Psychopharmacology · 2026Review
- Mitochondrial dysfunction at the intersection of alcohol use disorder and chronic pain.Function (Oxford, England) · 2026Review
- DEMOGRAPHIC PROFILE, SUBSTANCE USE TRENDS AND ASSOCIATED PSYCHOTIC DISORDERS AMONG VETERANS WITH MENTAL HEALTH CONDITIONS: A RETROSPECTIVE COHORT STUDY OF US VETERANS.ASEAN journal of psychiatry · 2024Article
- Mediation effect of hope on the relationship between inner strength and self-management in patients after percutaneous coronary intervention.Frontiers in psychology · 2024Article
- Mitochondria-wide association study observed significant interactions of mitochondrial respiratory and the inflammatory in the development of anxiety and depression.Translational psychiatry · 2023Article
- The influence of genetic and acquired factors on the vulnerability to develop depression: a review.Bioscience reports · 2023Review
- Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus Are Sex-Specific.International journal of molecular sciences · 2023Article
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Mitochondria as the target for disease related hormonal dysregulation.Brain, behavior, & immunity - health · 2021Article
- Altered estradiol-dependent cellular CaMolecular psychiatry · 2021Article
- The role of anthranilic acid in the increase of depressive symptoms and major depressive disorder during treatment for hepatitis C with pegylated interferon-α2a and oral ribavirin.Journal of psychiatry & neuroscience : JPN · 2021Article
- Gender Differences in Psychological Symptoms and Psychotherapeutic Processes in Japanese Children.International journal of environmental research and public health · 2020Article
- Sex differences in the genetic architecture of depression.Scientific reports · 2020Article
- Deciphering microbiome and neuroactive immune gene interactions in schizophrenia.Neurobiology of disease · 2020Review
- Mitochondria under the spotlight: On the implications of mitochondrial dysfunction and its connectivity to neuropsychiatric disorders.Computational and structural biotechnology journal · 2020Review
- Association between acute critical life events and the speed of onset of depressive episodes in male and female depressed patients.BMC psychiatry · 2018Observational
- Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression.Frontiers in neuroscience · 2018Review
- Ergosteryl 2-naphthoate, An Ergosterol Derivative, Exhibits Antidepressant Effects Mediated by the Modification of GABAergic and Glutamatergic Systems.Molecules (Basel, Switzerland) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The prevalence of some mental illnesses, including major depression, anxiety-, trauma-, and stress-related disorders, some substance use disorders, and later onset of schizophrenia, is higher in women than men. While the higher prevalence in women could simply be explained by socioeconomic determinants, such as income, social status, or cultural background, extensive studies show sex differences in biological, pharmacokinetic, and pharmacological factors contribute to females' vulnerability to these mental illnesses. In this review, we focus on estrogens, chronic stress, and neurotoxicity from behavioral, pharmacological, biological, and molecular perspectives to delineate the sex differences in these mental illnesses. Particularly, we investigate a possible role of mitochondrial function, including biosynthesis, bioenergetics, and signaling, on mediating the sex differences in psychiatric disorders.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.