ArticleBMC neuroscience2017
Effect of skilled reaching training and enriched environment on generation of oligodendrocytes in the adult sensorimotor cortex and corpus callosum.
Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 30 citations in OpenAlex.
- Distinct Physiological Mechanisms Drive Grey Matter Plasticity in Complex Versus Simple Sequence Learning.Human brain mapping · 2026Article
- Maintaining a Dynamic Brain: A Review of Empirical Findings Describing the Roles of Exercise, Learning, and Environmental Enrichment in Neuroplasticity from 2017-2023.Brain plasticity (Amsterdam, Netherlands) · 2024Review
- Remodelling of myelinated axons and oligodendrocyte differentiation is stimulated by environmental enrichment in the young adult brain.The European journal of neuroscience · 2022Article
- Article
- Direct Potential Modulation of Neurogenic Differentiation Markers by Granulocyte-Colony Stimulating Factor (G-CSF) in the Rodent Brain.Pharmaceutics · 2022Article
- Experience-dependent plasticity in early stations of sensory processing in mature brains: effects of environmental enrichment on dendrite measures in trigeminal nuclei.Brain structure & function · 2022Article
- Enriched Environment Effects on Myelination of the Central Nervous System: Role of Glial Cells.Neural plasticity · 2022Review
- The role of enriched environment in neural development and repair.Frontiers in cellular neuroscience · 2022Review
- Enriched Environment Enhances the Myelin Regulatory Factor by mTOR Signaling and Protects the Myelin Membrane Against Oxidative Damage in Rats Exposed to Chronic Immobilization Stress.Neurochemical research · 2021Article
- Clinical Applications of Myelin Plasticity for Remyelinating Therapies in Multiple Sclerosis.Annals of neurology · 2021Review
- Adult Neurogenesis and Stroke: A Tale of Two Neurogenic Niches.Frontiers in neuroscience · 2021Review
- Myelin plasticity: sculpting circuits in learning and memory.Nature reviews. Neuroscience · 2020Review
- Function and Mechanism of Myelin Regulation in Alcohol Abuse and Alcoholism.BioEssays : news and reviews in molecular, cellular and developmental biology · 2019Review
- Epigenomic signature of adrenoleukodystrophy predicts compromised oligodendrocyte differentiation.Brain pathology (Zurich, Switzerland) · 2018Article
- Advances in noninvasive myelin imaging.Developmental neurobiology · 2018Review
- How Do Cells of the Oligodendrocyte Lineage Affect Neuronal Circuits to Influence Motor Function, Memory and Mood?Frontiers in cellular neuroscience · 2018Review
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreased motor activity or social interactions through enriched environment are strong stimulators of grey and white matter plasticity in the adult rodent brain. In the present study we evaluated whether specific reaching training of the dominant forelimb (RT) and stimulation of unspecific motor activity through enriched environment (EE) influence the generation of distinct oligodendrocyte subpopulations in the sensorimotor cortex and corpus callosum of the adult rat brain. Animals were placed in three different housing conditions: one group was transferred to an EE, a second group received daily RT, whereas a third group remained in the standard cage. Bromodeoxyuridine (BrdU) was applied at days 2-6 after start of experiments and animals were allowed to survive for 10 and 42 days.
resultsEnriched environment and daily reaching training of the dominant forelimb significantly increased the number of newly differentiated GSTπ
conclusionsOur results indicate for the first time that specific and unspecific motor training conditions differentially alter the process of differentiation from oligodendrocyte subpopulations, in particular NG2
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