Evidence map›Paper›PMID 28279155›Full record

ArticleBMC infectious diseases2017

Acute dental infections managed in an outpatient parenteral antibiotic program setting: prospective analysis and public health implications.

William J Connors, Heidi H Rabie, Rafael L Figueiredo, Donna L Holton, Michael D Parkins

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. The use of panoramic radiographs to address the oral health needs of vulnerable Canadian populations.Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD · 2024
    Observational
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

William J ConnorsDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403, 29th Street NW, Room 303, 3rd Floor North Tower, Calgary, AB, T2N 2T9, Canada. wjaconno@ucalgary.ca.
Heidi H RabieDental Public Health Clinics, Alberta Health Services, Chumir Dental Clinic, 6th Floor, 1213 4th Street SW, Calgary, AB, T2R 0X7, Canada.
Rafael L FigueiredoPopulation, Public and Aboriginal Health, Alberta Health Services, Coronation Plaza 104, 14310 - 111 Avenue, Edmonton, AB, T5M 3Z7, Canada.
Donna L HoltonDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403, 29th Street NW, Room 303, 3rd Floor North Tower, Calgary, AB, T2N 2T9, Canada.
Michael D ParkinsDepartment of Medicine, University of Calgary, Foothills Medical Centre, 1403, 29th Street NW, Room 303, 3rd Floor North Tower, Calgary, AB, T2N 2T9, Canada.
Alberta Health Services · CAUniversity of Calgary · CAFoothills Medical Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of Acute Dental Infections (ADI) presenting for emergency department (ED) care are steadily increasing. Outpatient Parenteral Antibiotic Therapy (OPAT) programs are increasingly utilized as an alternative cost-effective approach to the management of serious infectious diseases but their role in the management of severe ADI is not established. This study aims to address this knowledge gap through evaluation of ADI referrals to a regional OPAT program in a large Canadian center.

methodsAll adult ED and OPAT program ADI referrals from four acute care adult hospitals in Calgary, Alberta, were quantified using ICD diagnosis codes in a regional reporting system. Citywide OPAT program referrals were prospectively enrolled over a five-month period from February to June 2014. Participants completed a questionnaire and OPAT medical records were reviewed upon completion of care.

resultsOf 704 adults presenting to acute care facilities with dental infections during the study period 343 (49%) were referred to OPAT for ADI treatment and 110 were included in the study. Participant mean age was 44 years, 55% were women, and a majority of participants had dental insurance (65%), had seen a dentist in the past six months (65%) and reported prior dental infections (77%), 36% reporting the current ADI as a recurrence. Median length of parenteral antibiotic therapy was 3 days, average total course of antibiotics was 15-days, with a cumulative 1326 antibiotic days over the study period. There was no difference in total duration of antibiotics between broad and narrow spectrum regimes. Conservative cost estimate of OPAT care was $120,096, a cost savings of $597,434 (83%) compared with hospitalization.

conclusionsADI represent a common preventable cause of recurrent morbidity. Although OPAT programs may offer short-term cost savings compared with hospitalization, risks associated with extended antibiotic exposures and delayed definitive dental management must also be gauged.

Indexed as

Acute DiseaseAdolescentAdultAgedAlbertaAmbulatory CareAnti-Bacterial AgentsCanadaCommunicable DiseasesCost-Benefit AnalysisFemaleHealth Care CostsHospitalizationHumansInfusions, ParenteralMaleAnti-Bacterial AgentsAntibioticsHealthcare costsOdontogenic infectionParenteral infusionsPeriapical abscessPublic health dentistry

Identifiers

PMID28279155
PMCPMC5345191
OpenAlexW2591821184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.