Evidence map›Paper›PMID 28279145›Full record

SynthesisTechnology in cancer research & treatment2017

Shorter GGN Repeats in Androgen Receptor Gene Would Not Increase the Risk of Prostate Cancer.

Jiatong Li, Feifan Xiao, Yuening Zhang, Aihua Lan, Qian Song, Ruoheng Zhang, Kailong Gu, Ping Chen, Zhuo Li, Xinhua Zhang and 1 more

Open access · bronzeAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Technology in cancer research & treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Molecular mechanisms involving prostate cancer racial disparity.American journal of clinical and experimental urology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jiatong Li1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Feifan Xiao1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Yuening Zhang1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Aihua Lan1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Qian Song3 First Clinical Academy, Guangxi Medical University, Nanning, Guangxi, China.
Ruoheng Zhang1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Kailong Gu1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Ping Chen4 Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Zhuo Li4 Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Xinhua Zhang4 Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China.
Xiaoli Yang1 Medical Scientific Research Center, Guangxi Medical University, Nanning, Guangxi, China.
Guangxi Medical University · CNWuhan University · CNFirst Affiliated Hospital of GuangXi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association between the polymorphic GGN repeat in androgen receptor gene and prostate cancer susceptibility has been studied extensively. But the results of these polymorphisms with prostate cancer risk remain inconclusive. Previous meta-analysis showed short GGN repeats (≤16 repeats) had high risks for prostate cancer compared with longer GGN repeats (>16 repeats). Many studies have been published since the release of the previous meta-analysis. Here, we conducted an updated meta-analysis to demonstrate whether short repeats have higher risks for prostate cancer compared to long repeats. Five databases (PubMed, EMBASE, Cochrane Library, The China National Knowledge Infrastructure, and Web of Science) were last searched until January 1, 2016. Random- or fixed-effects model was performed based on the heterogeneity among studies. The potential publication bias was assessed via Begg funnel plot and Egger regression test. Twelve out of 157 studies were extracted. The result indicated that there was no significant difference between short repeat group and long repeat group in the overall analysis ( I

Indexed as

Tandem Repeat SequencesGenetic Predisposition to DiseaseHumansMaleOdds RatioPolymorphism, GeneticProstatic NeoplasmsPublication BiasReceptors, AndrogenRiskReceptors, Androgenandrogen receptorgeneGGN repeatsmeta-analysisprostate cancer

Identifiers

PMID28279145
PMCPMC5616035
OpenAlexW2532531209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.