ArticleBJOG : an international journal of obstetrics and gynaecology2017
The association of protein intake (amount and type) with ovarian antral follicle counts among infertile women: results from the EARTH prospective study cohort.
Article in BJOG : an international journal of obstetrics and gynaecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00011713 (Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Human Exposure to Bisphenol A, Phthalates and Fertility, Pregnancy Outcomes.
Who cites it
17 citing papers in PubMed.
- Review
- Observational
- Associations between dietary patterns and parameters of ovarian reserve in Polish women of reproductive age.International journal of occupational medicine and environmental health · 2024Article
- High Carbohydrate, Fat, and Protein Diets Have a Critical Role in Folliculogenesis and Oocyte Development in Rats.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Healthy eating index and risk of diminished ovarian reserve: a case-control study.Scientific reports · 2024Article
- Do Popular Diets Impact Fertility?Nutrients · 2024Review
- BCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS.EMBO molecular medicine · 2023Article
- The Influence of Metabolic Factors and Diet on Fertility.Nutrients · 2023Review
- Dietary patterns are associated with improved ovarian reserve in overweight and obese women: a cross-sectional study of the Lifestyle and Ovarian Reserve (LORe) cohort.Reproductive biology and endocrinology : RB&E · 2022Article
- Prepregnancy adherence to plant-based diet indices and exploratory dietary patterns in relation to fecundability.The American journal of clinical nutrition · 2022Article
- Female Fertility and the Nutritional Approach: The Most Essential Aspects.Advances in nutrition (Bethesda, Md.) · 2021Article
- Can Nutrition Help in the Treatment of Infertility?Preventive nutrition and food science · 2021Review
- Low Intake of Vegetable Protein is Associated With Altered Ovulatory Function Among Healthy Women of Reproductive Age.The Journal of clinical endocrinology and metabolism · 2021Article
- Review
- Dietary patterns and ovarian reserve among women attending a fertility clinic.Fertility and sterility · 2020Article
- Relationship between nutrition and reproduction.Reproductive medicine and biology · 2020Review
- Article
Corrections and comments
- Commented on by
Authors and funding
8 authors.
Funding
Abstract
objectiveTo evaluate the association between protein intake (amount and type) and antral follicle count (AFC).
designProspective cohort.
settingAcademic fertility centre. POPULATION: Two hundred and sixty-five women undergoing fertility treatments at an academic fertility centre and participating in an ongoing study on environment and reproductive health.
methodsWe measured AFC in ultrasonographic evaluation among women undergoing infertility treatments. Women completed a previously validated semi-quantitative food frequency questionnaire. We used Poisson regression to evaluate the relation between protein intake and AFC while adjusting for age, body mass index, race, smoking status, and total energy intake.
main outcome measuresAntral follicle count.
resultsAmong 265 women (mean age: 35.0 ± 3.9 years, 85% Caucasian), total protein intake (% energy) was unrelated to AFC. When protein from different food sources was considered separately, we found a negative association between dairy protein intake and AFC. The mean AFC was 14.4% (3.9-23.7%) lower for women in the highest quintile of dairy protein intake than for women in the bottom quintile after adjusting for potential confounders (P-trend = 0.04). This association was stronger among women who had never smoked (P-trend = 0.002) but was not observed among previous smokers (P-trend = 0.36). There were no associations between protein intake from either non-dairy animal or vegetable sources and AFC.
conclusionHigher dairy protein intake (≥5.24% of energy) was associated with lower antral follicle counts among women presenting for infertility treatment. These findings should be further investigated in prospective studies also designed to clarify the biology underlying the observed associations. TWEETABLE ABSTRACT: Higher dairy protein intake was associated with lower antral follicle counts in an infertile population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.