Evidence map›Paper›PMID 28278309›Full record

ArticleThe review of diabetic studies : RDS2016

Mediterranean Diet and 10-year (2002-2012) Incidence of Diabetes and Cardiovascular Disease in Participants with Prediabetes: The ATTICA study.

Theodosios D Filippatos, Demosthenes B Panagiotakos, Ekavi N Georgousopoulou, Evangelia Pitaraki, Georgia-Maria Kouli, Christina Chrysohoou, Dimitrios Tousoulis, Christodoulos Stefanadis, Christos Pitsavos, ATTICA Study Group

Open access · bronzeAbstract read
In one paragraph

Article in The review of diabetic studies : RDS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 7 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 7 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Theodosios D FilippatosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Demosthenes B PanagiotakosDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Ekavi N GeorgousopoulouDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Evangelia PitarakiDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Georgia-Maria KouliDepartment of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.
Christina ChrysohoouFirst Cardiology Clinic, School of Medicine, University of Athens, Greece.
Dimitrios TousoulisFirst Cardiology Clinic, School of Medicine, University of Athens, Greece.
Christodoulos StefanadisFirst Cardiology Clinic, School of Medicine, University of Athens, Greece.
Christos PitsavosFirst Cardiology Clinic, School of Medicine, University of Athens, Greece.
ATTICA Study Group
Harokopio University of Athens · GRNational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrediabetes has been related to an increased risk of developing diabetes and cardiovascular disease (CVD).

aimThe aim of the present study was to examine the effect of the Mediterranean diet on diabetes and CVD risk in subjects with impaired fasting glucose (IFG, i.e. fasting plasma glucose 100-125 mg/dl).

methodsDuring 2001-2002, 3042 men and women (>18y) were enrolled for the study. The participants showed no clinical evidence of CVD or any other chronic disease, and were living in the greater Athens (Greece) area. In 2011 and 2012, the 10-year follow-up examinations were performed, including a working sample of n = 1875 participants without diabetes at baseline. Adherence to the Mediterranean diet at baseline evaluation was assessed using the MedDietScore (range 0-55).

resultsThe prediabetic subjects (n = 343) had a significantly higher incidence of diabetes (25% vs. 10%, p < 0.001) and CVD (17.8% vs. 12.3%, p = 0.007) compared with subjects with normal glucose values. A significant trend towards lower diabetes and CVD incidence was observed with medium and high adherence to the Mediterranean diet compared with low adherence (p < 0.001). High adherence to the Mediterranean diet (>35/55 score) was associated with lower 10-year incidence of diabetes and CVD. In multiple logistic regression models, participants with high levels of adherence to the Mediterranean diet were significantly less affected by diabetes and CVD than those with low adherence levels.

conclusionHigh adherence to the Mediterranean diet is associated with a low risk of developing diabetes and CVD in prediabetic subjects.

Indexed as

Diet, MediterraneanPatient ComplianceUrban HealthAdultBiomarkersBlood GlucoseCardiovascular DiseasesCohort StudiesDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGreeceHumansIncidenceMaleMiddle AgedBiomarkersBlood Glucose

Identifiers

PMID28278309
PMCPMC5734223
OpenAlexW2975430135

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.