Evidence map›Paper›PMID 28278208›Full record

ArticlePloS one2017

Parallel group independent component analysis for massive fMRI data sets.

Shaojie Chen, Lei Huang, Huitong Qiu, Mary Beth Nebel, Stewart H Mostofsky, James J Pekar, Martin A Lindquist, Ani Eloyan, Brian S Caffo

Abstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Big Data and Neuroimaging.Statistics in biosciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaojie ChenDepartment of Biostatistics, Johns Hopkins University, Baltimore, United States of America.ORCID http://orcid.org/0000-0002-3543-8964
Lei HuangDepartment of Biostatistics, Johns Hopkins University, Baltimore, United States of America.
Huitong QiuDepartment of Biostatistics, Johns Hopkins University, Baltimore, United States of America.
Mary Beth NebelKennedy Krieger Institute, Baltimore, United States of America.
Stewart H MostofskySchool of Medicine, Johns Hopkins University, Baltimore, United States of America.
James J PekarKennedy Krieger Institute, Baltimore, United States of America.
Martin A LindquistDepartment of Biostatistics, Johns Hopkins University, Baltimore, United States of America.
Ani EloyanDepartment of Biostatistics, Brown University, Providence, Rhode Island, United States of America.
Brian S CaffoDepartment of Biostatistics, Johns Hopkins University, Baltimore, United States of America.

Funding

TR&D 4: Algorithms for functional and anatomical brain analysisP41EB015909 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI VAN ZIJL, PETER CM · 2012 to 2020
$13.1M
Statistical Methods for Multilevel Multivariate Functional StudiesR01NS060910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Ciprian M Crainiceanu · 2009 to 2026
$8.3M
Anomalous Motor Physiology In ADHDR01MH078160 · NIMH · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI MOSTOFSKY, STEWART H · 2006 to 2024
$5.8M
Longitudinal Causal Inferencer for fMRIR01EB016061 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI LINDQUIST, MARTIN · 2013 to 2020
$2.3M
Statistical methods for large n and p problemsR01EB012547 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI CAFFO, BRIAN SCOTT · 2010 to 2016
$2.1M
Large-scale Network Modeling for Brain Dynamics: Statistical Learning and OptimizationR01EB022911 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI LUO, XI · 2016 to 2018
$1.2M
NIBIB NIH HHS P41 EB015909NIBIB NIH HHS R01 EB012547NIBIB NIH HHS R01 EB016061NIMH NIH HHS R01 MH078160NINDS NIH HHS R01 NS060910
6 · The paper itself

Abstract

Independent component analysis (ICA) is widely used in the field of functional neuroimaging to decompose data into spatio-temporal patterns of co-activation. In particular, ICA has found wide usage in the analysis of resting state fMRI (rs-fMRI) data. Recently, a number of large-scale data sets have become publicly available that consist of rs-fMRI scans from thousands of subjects. As a result, efficient ICA algorithms that scale well to the increased number of subjects are required. To address this problem, we propose a two-stage likelihood-based algorithm for performing group ICA, which we denote Parallel Group Independent Component Analysis (PGICA). By utilizing the sequential nature of the algorithm and parallel computing techniques, we are able to efficiently analyze data sets from large numbers of subjects. We illustrate the efficacy of PGICA, which has been implemented in R and is freely available through the Comprehensive R Archive Network, through simulation studies and application to rs-fMRI data from two large multi-subject data sets, consisting of 301 and 779 subjects respectively.

Indexed as

Magnetic Resonance ImagingAdolescentAdultAutism Spectrum DisorderBrain MappingChildHumansImage Processing, Computer-AssistedNeuroimagingYoung Adult

Identifiers

PMID28278208
PMCPMC5344430

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.