Evidence map›Paper›PMID 28278184›Full record

ReviewPLoS pathogens2017

The human immune response to Toxoplasma: Autophagy versus cell death.

Shruthi Krishnamurthy, Eleni K Konstantinou, Lucy H Young, Daniel A Gold, Jeroen P J Saeij

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Surface antigen SAG1 mediatesInfection and immunity · 2025
    Article
  2. Vaccines · 2025
    Review
  3. Article
  4. p97/VCP targetsmSphere · 2023
    Article
  5. Article
  6. Review
  7. Frontiers in immunology · 2022
    Article
  8. Article
  9. Host autophagy limitsFrontiers in microbiology · 2022
    Article
  10. Review
  11. Article
  12. Spermatogonia apoptosis induction as a possible mechanism ofIranian journal of basic medical sciences · 2020
    Article
  13. Article
  14. The Host Autophagy DuringFrontiers in microbiology · 2020
    Review
  15. Assays to Evaluate Toxoplasma-Macrophage Interactions.Methods in molecular biology (Clifton, N.J.) · 2020
    Article
  16. EXCLI journal · 2020
    Article
  17. Article
  18. Long-Term Impact ofFrontiers in cellular and infection microbiology · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shruthi KrishnamurthyDepartment of Pathology, Microbiology and Immunology, University of California Davis, Davis, California, United States of America.ORCID 0000-0003-4540-6613
Eleni K KonstantinouDepartment of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0002-7155-5770
Lucy H YoungDepartment of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America.ORCID 0000-0001-8634-7512
Daniel A GoldDepartment of Pathology, Microbiology and Immunology, University of California Davis, Davis, California, United States of America.
Jeroen P J SaeijDepartment of Pathology, Microbiology and Immunology, University of California Davis, Davis, California, United States of America.ORCID 0000-0003-0289-7109

Funding

Toxoplasma strain-specific modulation of mouse immune cellsR01AI080621 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SAEIJ, JEROEN · 2009 to 2018
$3.6M
Inhibiting Toxoplasma growth by disrupting its access to host small moleculesR21AI114930 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SAEIJ, JEROEN · 2015 to 2016
$445k
A serological test to determine strains associated with ocular toxoplasmosisR21EY024593 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SAEIJ, JEROEN · 2015 to 2016
$430k
NEI NIH HHS R21 EY024593NIAID NIH HHS R01 AI080621NIAID NIH HHS R21 AI114930NIH HHS R01AI080621-06A1NIH HHS R21AI114930-01NIH HHS R21EY024593-01A1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAutophagyCell DeathHumansMiceToxoplasmaToxoplasmosis

Identifiers

PMID28278184
PMCPMC5344534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.