Evidence map›Paper›PMID 28278051›Full record

ArticleCell cycle (Georgetown, Tex.)2017

Bcl-2 delays cell cycle through mitochondrial ATP and ROS.

Xing Du, Xufeng Fu, Kun Yao, Zhenwei Lan, Hui Xu, Qinghua Cui, Elizabeth Yang

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. BCL-2 and BCL-xL in Cancer: Regulation, Function, and Therapeutic Targeting.International journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. HDL-Chitosan Nanoparticles for siRNA Delivery as an SR-B1 Receptor Targeted System.Combinatorial chemistry & high throughput screening · 2023
    Article
  13. Article
  14. Article
  15. GOncology letters · 2021
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xing Dua School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Xufeng Fua School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Kun Yaoa School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Zhenwei Lana School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Hui Xua School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Qinghua Cuia School of Life Sciences , Yunnan University , Kunming , Yunnan , P.R. China.
Elizabeth Yangc Center for Cancer and Blood Disorders of Northern Virginia , Falls Church , VA , USA.
Yunnan University · CNCenter for Cancer and Blood Disorders · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bcl-2 inhibits cell proliferation by delaying G

Indexed as

Cell CycleAdenosine TriphosphateAnimalsCell Cycle CheckpointsCyclin-Dependent Kinase Inhibitor p27HEK293 CellsHumansMiceMitochondriaNIH 3T3 CellsProto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesS PhaseUp-RegulationAdenosine TriphosphateCyclin-Dependent Kinase Inhibitor p27Proto-Oncogene Proteins c-bcl-2Reactive Oxygen SpeciesATPBcl-2cell cycleP27ROS

Identifiers

PMID28278051
PMCPMC5397261
OpenAlexW2589302412

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.