Evidence map›Paper›PMID 28277934›Full record

ReviewRNA biology2017

The modified base isopentenyladenosine and its derivatives in tRNA.

Ulrich Schweizer, Simon Bohleber, Noelia Fradejas-Villar

Open access · bronzeAbstract readReview
In one paragraph

Review in RNA biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed, 130 citations in OpenAlex.

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  5. Probing the function ofMicrobiology spectrum · 2026
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24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ulrich Schweizera Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn , Bonn , Germany.ORCID 0000-0003-1380-4780
Simon Bohlebera Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn , Bonn , Germany.ORCID 0000-0002-1551-9839
Noelia Fradejas-Villara Institut für Biochemie und Molekularbiologie, Rheinische Friedrich-Wilhelms-Universität Bonn , Bonn , Germany.ORCID 0000-0003-3418-0743
University of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Base 37 in tRNA, 3'-adjacent to the anticodon, is occupied by a purine base that is thought to stabilize codon recognition by stacking interactions on the first Watson-Crick base pair. If the first codon position forms an A.U or U.A base pair, the purine is likely further modified in all domains of life. One of the first base modifications found in tRNA is N

Indexed as

AnimalsAnticodonBacteriaCodonDisease SusceptibilityHumansIsopentenyladenosineMethylationMitochondriaPurinesRNA, TransferStructure-Activity RelationshipSubstrate SpecificityYeastsAnticodonCodonIsopentenyladenosinePurinesRNA, Transferi6AmiaAmitochondriamod5modificationselenoproteinTRIT1tRNA

Identifiers

PMID28277934
PMCPMC5699536
OpenAlexW2587842150

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.